Relevance of in vitro antimicrobial susceptibility of Brucella melitensis to relapse rate in human brucellosis.
J Ariza, J Bosch, F Gudiol, J Liñares, P F Viladrich, R Martín
The in vitro susceptibility of Brucella melitensis was examined vis-a-vis the clinical outcome in 75 patients with brucellosis . The initial MICs for Brucella isolates from patients who relapsed and from those who did not were similar. Furthermore, the MICs for isolates from patients whose infections relapsed were no different from those for original isolates. Our results clearly showed that neither initial nor subsequent antibiotic susceptibility plays a role in the likelihood of relapse of patients with brucellosis .
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Adolescent
Adult
Aged
Aged, 80 and over
Anti-Bacterial Agents
Brucella
Brucellosis
Child
Doxycycline
Drug Resistance, Microbial
Female
Humans
Male
Microbial Sensitivity Tests
Middle Aged
Prospective Studies
Recurrence
Rifampin
Streptomycin
Tetracycline
Anti-Bacterial Agents
Tetracycline
Doxycycline
Rifampin
Streptomycin
