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Canadian Medical Association journal
Jul 08, 1972;107 (1): 38-41.

Chlormadinone acetate and its effect on the hemostatic mechanism.

A M Wodzicki, A T Coopland
Author Information
PMID: 4114470

Abstract

There is an apparent discrepancy between the effects on the hemostatic mechanism of synthetic progestins alone and synthetic progestins in combination with synthetic estrogens. Coagulation studies were carried out on 21 patients treated with chlormadinone acetate 0.5 mg. on a continuous daily basis for 12 weeks in order to determine its effects on hemostasis. Unlike the standard estrogen/progestin contraceptive agents, this synthetic progestin appears to have no effect on the coagulation system as determined by standard laboratory tests.

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MeSH Term

Blood Coagulation
Blood Coagulation Factors
Blood Platelets
Chlormadinone Acetate
Contraceptives, Oral
Female
Fibrinogen
Fibrinolysis
Hemorrhage
Hemostasis
Humans
Immunodiffusion
Uterus

Chemicals

Blood Coagulation Factors
Contraceptives, Oral
Chlormadinone Acetate
Fibrinogen
Journal Article

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