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Applied and environmental microbiology
Mar, 1983;45 (3): 1119-21.

Improved facility and sensitivity in the use of guinea pigs for the isolation of Legionella pneumophila from cooling tower water.

E D Leinbach, H H Winkler, D O Wood, J H Coggin
Author Information
PMID: 6342532 DOI: 10.1128/aem.45.3.1119-1121.1983

Abstract

The established criteria for the determination of the optimum time for the sacrifice of guinea pigs inoculated with samples of cooling tower water were found to be inadequate for the detection of low levels of Legionella pneumophila. By ignoring the requirement for fever and by sequentially sacrificing the infected guinea pigs on days 3 through 5 postinoculation, we simplified the procedure, and the sensitivity of detection was improved a great deal.

References

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MeSH Term

Air Conditioning
Animals
Bacteriological Techniques
Guinea Pigs
Legionella
Male
Water Microbiology
Journal Article Research Support, Non-U.S. Gov't

Word Cloud

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