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Infection and immunity
Jun, 1994;62 (6): 2639-43.

Diversity of the P2 protein among nontypeable Haemophilus influenzae isolates.

J Bell, S Grass, D Jeanteur, R S Munson
Author Information
  1. J Bell: Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri.
PMID: 8188390 DOI: 10.1128/iai.62.6.2639-2643.1994

Abstract

The genes for outer membrane protein P2 of four nontypeable Haemophilus influenzae strains were cloned and sequenced. The derived amino acid sequences were compared with the outer membrane protein P2 sequence from H. influenzae type b MinnA and the sequences of P2 from three additional nontypeable H. influenzae strains. The sequences were 76 to 94% identical. The sequences had regions with considerable variability separated by regions which were highly conserved. The variable regions mapped to putative surface-exposed loops of the protein.

Associated Data

GENBANK | U08205; U08206; U08207; U08208

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Grants

  1. R01-AI-17572/NIAID NIH HHS

MeSH Term

Amino Acid Sequence
Bacterial Outer Membrane Proteins
Cloning, Molecular
DNA, Bacterial
Haemophilus influenzae
Molecular Sequence Data

Chemicals

Bacterial Outer Membrane Proteins
DNA, Bacterial
Journal Article Research Support, U.S. Gov't, P.H.S.

Word Cloud

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