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Medizinische Klinik (Munich, Germany : 1983)
Apr 15, 1997;92 (4): 221-7.

[Definition of "chronic fatigue syndrome" (CFS)].

U Heyll, P Wachauf, V Senger, M Diewitz
Author Information
  1. U Heyll: Gesellschaftsärztliche Abteilung der Deutschen Krankenversicherung, Köln.
PMID: 9221305 DOI: 10.1007/BF03043262

Abstract

The definition of "Chronic fatigue Syndrome" (CFS) in 1988 was an attempt to establish a uniform basis for the previously heterogeneous approaches to research of this severe and inexplicable state of fatigue. At the same time, researchers wished to narrow down a pathogenetically founded disease entity a priori by specifying precise disease criteria. The empirical data gathered in accordance with the CFS definition, however, have failed to confirm the assumption that the disease entity is pathogenetically uniform. Furthermore, the originally selected criteria have proven to be impracticable ore theoretically questionable. In the period that followed, modifications that permitted a more comprehensive and yet more differentiated classification of fatigue states of unclear etiology were proposed. The new research approach avoids postulation of causal entities and puts CFS back in a category with other descriptive states of fatigue.

References

  1. J Clin Psychiatry. 1989 Feb;50(2):53-6 [PMID: 2536690]
  2. Lancet. 1994 Sep 24;344(8926):864-8 [PMID: 7916407]
  3. JAMA. 1987 May 1;257(17):2297-302 [PMID: 3033337]
  4. BMJ. 1993 Jul 10;307(6896):103-6 [PMID: 8343705]
  5. BMJ. 1994 Mar 19;308(6931):763-6 [PMID: 7908238]
  6. Blood. 1948 Aug;3(8):858-61 [PMID: 18873530]
  7. Arch Intern Med. 1993 Dec 27;153(24):2759-65 [PMID: 8257251]
  8. Am J Hyg. 1950 Sep;52(2):222-38 [PMID: 14771044]
  9. N Engl J Med. 1957 Aug 22;257(8):345-55 [PMID: 13464938]
  10. Lancet. 1957 Apr 13;272(6972):757-8 [PMID: 13417586]
  11. Clin Infect Dis. 1994 Jan;18 Suppl 1:S11-5 [PMID: 8148436]
  12. Med J Aust. 1988 Jan 18;148(2):80-2 [PMID: 3336341]
  13. J Infect. 1985 May;10(3):211-22 [PMID: 2993423]
  14. N Engl J Med. 1988 Dec 29;319(26):1726-8 [PMID: 2849719]
  15. Ann Intern Med. 1992 Aug 15;117(4):325-31 [PMID: 1322076]
  16. Lancet. 1954 Nov 20;267(6847):1044-8 [PMID: 13213112]
  17. Med J Aust. 1990 Nov 5;153(9):522-8 [PMID: 2233474]
  18. Br Med J (Clin Res Ed). 1988 Mar 5;296(6623):696-9 [PMID: 3128374]
  19. Am J Med. 1959 Apr;26(4):569-95 [PMID: 13637100]
  20. Ann Intern Med. 1988 Mar;108(3):387-9 [PMID: 2829679]
  21. Dtsch Med Wochenschr. 1993 Sep 24;118(38):1373-80 [PMID: 8404480]
  22. Ann Intern Med. 1994 Dec 15;121(12):953-9 [PMID: 7978722]
  23. Lancet. 1993 Nov 13;342(8881):1247-8 [PMID: 7901572]
  24. Dtsch Med Wochenschr. 1996 Sep 20;121(38):1165-8 [PMID: 8925737]
  25. Lancet. 1957 Dec 14;273(7007):1196-200 [PMID: 13492606]
  26. Science. 1986 Oct 31;234(4776):541-2 [PMID: 3020689]
  27. Lancet. 1988 Jun 4;1(8597):1286-7 [PMID: 2897549]
  28. Arch Intern Med. 1995 Jan 9;155(1):97-103 [PMID: 7632202]
  29. Fortschr Neurol Psychiatr. 1996 Apr;64(4):132-41 [PMID: 8655125]
  30. Med Klin (Munich). 1994 Mar 15;89(3):154-9 [PMID: 8196576]
  31. BMJ. 1994 Mar 19;308(6931):756-9 [PMID: 8142830]
  32. J R Coll Gen Pract. 1987 May;37(298):212-4 [PMID: 3320358]
  33. JAMA. 1987 May 1;257(17):2303-7 [PMID: 3033338]
  34. Internist (Berl). 1995 Dec;36(12):1156-61 [PMID: 8567221]
  35. J Psychosom Res. 1994 Jul;38(5):383-92 [PMID: 7965927]
  36. BMJ. 1994 Mar 19;308(6931):732-3 [PMID: 8142823]
  37. Med J Aust. 1989 Aug 7;151(3):122-4 [PMID: 2787888]
  38. Arch Intern Med. 1992 Aug;152(8):1569-70 [PMID: 1323245]
  39. N Engl J Med. 1959 Apr 9;260(15):757-64 contd [PMID: 13644582]
  40. Br Med J. 1970 Jan 3;1(5687):11-5 [PMID: 5411596]
  41. BMJ. 1994 Mar 19;308(6931):776-7 [PMID: 8142836]
  42. N Engl J Med. 1957 Aug 22;257(8):356-64 [PMID: 13464939]
  43. J R Soc Med. 1991 Feb;84(2):118-21 [PMID: 1999813]
  44. Am J Med. 1996 Jan;100(1):56-64 [PMID: 8579088]
  45. South Med J. 1984 Nov;77(11):1376-82 [PMID: 6093268]
  46. Dtsch Med Wochenschr. 1995 Jan 5;120(1-2):47 [PMID: 7821206]
  47. Clin Infect Dis. 1994 Jan;18 Suppl 1:S43-8 [PMID: 8148452]
  48. Am J Med. 1994 Jun;96(6):544-50 [PMID: 8017453]
  49. Br Med J. 1970 Jan 3;1(5687):7-11 [PMID: 5411611]
  50. J Infect Dis. 1994 Jul;170(1):1-6 [PMID: 8014482]
  51. Arch Intern Med. 1992 Aug;152(8):1604-9 [PMID: 1497394]
  52. Lancet. 1987 Jan 24;1(8526):218-9 [PMID: 2880043]

MeSH Term

Diagnosis, Differential
Fatigue Syndrome, Chronic
Humans
English Abstract Journal Article Review

Word Cloud

Created with Highcharts 10.0.0CFSfatiguediseasedefinitionuniformresearchpathogeneticallyentitycriteriastates"ChronicFatigueSyndrome"1988attemptestablishbasispreviouslyheterogeneousapproachessevereinexplicablestatetimeresearcherswishednarrowfoundedpriorispecifyingpreciseempiricaldatagatheredaccordancehoweverfailedconfirmassumptionFurthermoreoriginallyselectedprovenimpracticableoretheoreticallyquestionableperiodfollowedmodificationspermittedcomprehensiveyetdifferentiatedclassificationunclearetiologyproposednewapproachavoidspostulationcausalentitiesputsbackcategorydescriptive[Definition"chronicsyndrome"]

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