Detection rate of Cryptococcus neoformans in cerebrospinal fluid specimens at Kenyatta National Hospital, Nairobi.

F A Odhiambo, E M Murage, W Ngare, J O Ndinya-Achola
Author Information
  1. F A Odhiambo: Department of Medical Microbiology, University of Nairobi, Nairobi.

Abstract

A ten-year retrospective review of laboratory detection of Cryptococcus neoformans in cerebrospinal fluid was undertaken using past laboratory and clinical records at Kenyatta National Hospital. A total of 1462 India-ink tests were carried out, 76 (5.2%) of these tested positive for C. neoformans. An increasing number of clinical requests for India-ink test mirrored by increasing number of patients with immunological disorders were noted over the study period although no obvious trend emerged in the detection pattern of C. neoformans. The use of a more sensitive test such as the latex agglutination technique is suggested.

MeSH Term

Adolescent
Adult
Aged
Aged, 80 and over
Carbon
Clinical Laboratory Techniques
Coloring Agents
Cryptococcosis
Female
Hospitals, Teaching
Hospitals, Urban
Humans
Kenya
Laboratories, Hospital
Male
Middle Aged
Reproducibility of Results
Retrospective Studies
Sensitivity and Specificity

Chemicals

Coloring Agents
chinese ink
Carbon

Word Cloud

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