Emerging targets for the development of novel antifungal therapeutics.

A H Groll, A J De Lucca, T J Walsh
Author Information
  1. A H Groll: Immunocompromised Host Section, National Cancer Institute, NIH, Bethesda, MD, USA.

Abstract

Invasive mycoses have become important causes of morbidity and mortality in immunocompromised patients. New approaches for antifungal therapy are required to meet the challenges imposed by these life-threatening infections. Such approaches are being developed through identification of novel biochemical and molecular targets of pathogenic fungi.

MeSH Term

Antifungal Agents
Cell Membrane
Cell Wall
DNA, Fungal
Fungal Proteins
Peptide Elongation Factors
Signal Transduction

Chemicals

Antifungal Agents
DNA, Fungal
Fungal Proteins
Peptide Elongation Factors

Word Cloud

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