- J Pupo Nogueira Neto: Department of Dermatology of the Pontifìcia Universidade Catòlica de Campinas, Rua Maria Monteiro 1572, POBox 13025-152, Cambui, Campinas - SP, Brazil.
American cutaneous leishmaniasis, a disease of great worldwide importance, especially on the American continent, has had its epidemological modifications. These are revised and discussed in view of the current situation of recent increase in its incidence in regions with low morbidity since 1950, where no apparent cause that would justify an epidemic outbreak could be found. We analysed the causes of these alterations and the profile now seen in the State of Sao Paulo, Brazil.