Electronic structure of wet DNA.

Francesco Luigi Gervasio, Paolo Carloni, Michele Parrinello
Author Information
  1. Francesco Luigi Gervasio: Università di Firenze, Dipartimento di Chimica, Via della Lastruccia 3, I-50019 Sesto Fiorentino, Italy.

Abstract

The electronic properties of a Z-DNA crystal synthesized in the laboratory are investigated by means of density-functional theory Car-Parrinello calculations. The electronic structure has a gap of only 1.28 eV. This separates a manifold of 12 occupied states which came from the pi guanine orbitals from the lowest empty states in which the electron is transferred to the Na+ from PO-4 groups and water molecules. We have evaluated the anisotropic optical conductivity. At low frequency the conductivity is dominated by the pi-->Na+ transitions. Our calculation demonstrates that the cost of introducing electron holes in wet DNA strands could be lower than previously anticipated.

MeSH Term

Crystallization
DNA
Hydrogen Bonding
Nucleic Acid Conformation
Oligonucleotides
Water

Chemicals

Oligonucleotides
Water
DNA

Word Cloud

Created with Highcharts 10.0.0electronicstructurestateselectronconductivitywetDNApropertiesZ-DNAcrystalsynthesizedlaboratoryinvestigatedmeansdensity-functionaltheoryCar-Parrinellocalculationsgap128eVseparatesmanifold12occupiedcamepiguanineorbitalslowestemptytransferredNa+PO-4groupswatermoleculesevaluatedanisotropicopticallowfrequencydominatedpi-->Na+transitionscalculationdemonstratescostintroducingholesstrandslowerpreviouslyanticipatedElectronic

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