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Journal of bacteriology
Feb, 2004;186 (3): 889-93.

Expression of Vibrio vulnificus capsular polysaccharide inhibits biofilm formation.

Lavin A Joseph, Anita C Wright
Author Information
  1. Lavin A Joseph: Aquatic Food Products Laboratory, Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida 32611, USA.
PMID: 14729720 DOI: 10.1128/JB.186.3.889-893.2004

Abstract

Vibrio vulnificus is a human pathogen that produces lethal septicemia in susceptible persons, and the primary virulence factor for this organism is capsular polysaccharide (CPS). The role of the capsule in V. vulnificus biofilms was examined under a variety of conditions, by using either defined CPS mutants or spontaneous CPS expression phase variants derived from multiple strains. CPS expression was shown to inhibit attachment and biofilm formation, which contrasted with other studies describing polysaccharides as integral to biofilms in related species.

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MeSH Term

Bacterial Adhesion
Bacterial Capsules
Biofilms
Vibrio vulnificus
Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.
Article has an altmetric score of 6

Word Cloud

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