Sarcoidosis mimicking ischaemic ventricular arrhythmia and pulmonary embolism.

C P C de Jager, E R Jessurun, E K Jansen, J Verheij, A R J Girbes, R J M Strack van Schijndel
Author Information
  1. C P C de Jager: Department of Intensive Care, VU University Medical Centre, Amsterdam, The Netherlands. P.de.jager@jbz.nl

Abstract

Sarcoidosis is a multisystem granulomatous disorder characterised pathologically by the presence of noncaseating granulomas in the organs involved. Cardiac involvement, although well known, is rare. We describe a 72-year-old patient who was admitted to the intensive care unit after coronary artery bypass grafting. She developed refractory right and left ventricular failure complicated by multiple organ failure and died three days later. Postmortem examination revealed extensive sarcoidosis. On hindsight, preoperative ventricular tachycardia and an abnormal perfusion-ventilation scintigraphy of the lungs were manifestations of an underlying sarcoidosis.

MeSH Term

Aged
Biopsy, Needle
Coronary Angiography
Coronary Artery Bypass
Diagnosis, Differential
Disease Progression
Emergency Service, Hospital
Fatal Outcome
Female
Heart Diseases
Humans
Immunohistochemistry
Myocardial Ischemia
Pulmonary Embolism
Sarcoidosis
Tachycardia, Ventricular

Word Cloud

Created with Highcharts 10.0.0ventricularSarcoidosisfailuresarcoidosismultisystemgranulomatousdisordercharacterisedpathologicallypresencenoncaseatinggranulomasorgansinvolvedCardiacinvolvementalthoughwellknownraredescribe72-year-oldpatientadmittedintensivecareunitcoronaryarterybypassgraftingdevelopedrefractoryrightleftcomplicatedmultipleorgandiedthreedayslaterPostmortemexaminationrevealedextensivehindsightpreoperativetachycardiaabnormalperfusion-ventilationscintigraphylungsmanifestationsunderlyingmimickingischaemicarrhythmiapulmonaryembolism

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