High-frequency phase variation of Vibrio vulnificus 1003: isolation and characterization of a rugose phenotypic variant.

Brenda L Grau, Margaret C Henk, Gregg S Pettis
Author Information
  1. Brenda L Grau: Department of Biological Sciences, 107 Life Sciences Building, Louisiana State University, Baton Rouge, LA 70803, USA. bgrau1@lsu.edu

Abstract

The marine bacterium Vibrio vulnificus is a human pathogen that can spontaneously switch between virulent opaque and avirulent translucent phenotypes. Here, we document an additional form, the rugose variant, which produces copious biofilms and which may contribute both to pathogenicity of V. vulnificus and to its survival under adverse environmental conditions.

References

  1. Microbiol Mol Biol Rev. 2000 Dec;64(4):847-67 [PMID: 11104821]
  2. Microbes Infect. 2000 Feb;2(2):177-88 [PMID: 10742690]
  3. J Bacteriol. 2001 Mar;183(5):1716-26 [PMID: 11160103]
  4. Appl Environ Microbiol. 2001 Sep;67(9):4048-56 [PMID: 11526004]
  5. Appl Environ Microbiol. 2001 Oct;67(10):4717-25 [PMID: 11571177]
  6. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3129-34 [PMID: 11854465]
  7. Appl Environ Microbiol. 2002 Nov;68(11):5773-8 [PMID: 12406780]
  8. J Bacteriol. 2002 Dec;184(23):6481-9 [PMID: 12426335]
  9. Infect Immun. 2003 Mar;71(3):1091-7 [PMID: 12595419]
  10. Clin Infect Dis. 2003 Jul 15;37(2):272-80 [PMID: 12856219]
  11. Genome Res. 2003 Dec;13(12):2577-87 [PMID: 14656965]
  12. J Bacteriol. 2004 Feb;186(3):889-93 [PMID: 14729720]
  13. Appl Environ Microbiol. 2004 Apr;70(4):2486-93 [PMID: 15066847]
  14. Infect Immun. 1981 May;32(2):964-6 [PMID: 6788703]
  15. J Gen Microbiol. 1984 Oct;130(10):2741-3 [PMID: 6512503]
  16. Infect Immun. 1985 Feb;47(2):446-51 [PMID: 2578434]
  17. Infect Immun. 1987 Jan;55(1):269-72 [PMID: 2432016]
  18. Infect Immun. 1990 Jun;58(6):1769-73 [PMID: 2160432]
  19. J Clin Microbiol. 1991 Aug;29(8):1684-8 [PMID: 1761690]
  20. Lancet. 1992 Sep 19;340(8821):740 [PMID: 1355849]
  21. Int J Syst Bacteriol. 1996 Oct;46(4):1088-92 [PMID: 8863440]
  22. J Infect Dis. 1996 Dec;174(6):1364-8 [PMID: 8940236]
  23. Appl Environ Microbiol. 1997 Aug;63(8):3308-10 [PMID: 9251221]
  24. Nucleic Acids Res. 1997 Sep 1;25(17):3389-402 [PMID: 9254694]
  25. Infect Immun. 1998 Jun;66(6):2601-6 [PMID: 9596722]
  26. Appl Environ Microbiol. 1998 Oct;64(10):3648-55 [PMID: 9758780]
  27. Infect Immun. 1999 Feb;67(2):958-63 [PMID: 9916115]
  28. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):4028-33 [PMID: 10097157]
  29. Infect Immun. 1999 May;67(5):2250-7 [PMID: 10225881]
  30. Science. 1999 May 21;284(5418):1318-22 [PMID: 10334980]
  31. FEMS Microbiol Lett. 1999 May 15;174(2):207-14 [PMID: 10339810]
  32. J Bacteriol. 2001 Jan;183(2):758-62 [PMID: 11133972]

MeSH Term

Biofilms
Phenotype
Vibrio vulnificus

Word Cloud

Created with Highcharts 10.0.0vulnificusVibriorugosevariantmarinebacteriumhumanpathogencanspontaneouslyswitchvirulentopaqueavirulenttranslucentphenotypesdocumentadditionalformproducescopiousbiofilmsmaycontributepathogenicityVsurvivaladverseenvironmentalconditionsHigh-frequencyphasevariation1003:isolationcharacterizationphenotypic

Similar Articles

Cited By