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Nucleic acids research
Jan 01, 2006;34 (Database issue): D398-401.

ShiBASE: an integrated database for comparative genomics of Shigella.

Jian Yang, Lihong Chen, Jun Yu, Lilian Sun, Qi Jin
Author Information
  1. Jian Yang: State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100176, China.
PMID: 16381896 DOI: 10.1093/nar/gkj033

Abstract

Among the major enteric bacterial pathogens, Shigella is found to display extreme genome diversity and dynamics, which imposes a challenge in comparative genomic studies. To facilitate further studies in this area, we have constructed an integrated online database, ShiBASE (http://www.mgc.ac.cn/ShiBASE/),which contains Shigella genomic sequences of four species and additional comparative genomic hybridization (CGH) data of 43 serotypes. ShiBASE offers online comparative analysis on DNA sequences, gene orders, metabolic pathways and virulence factors. In addition, ShiBASE has a newly developed online comparative visualization service, Shi-align, which enables the alignment of any query sequence with the reference genome sequences.

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MeSH Term

Databases, Nucleic Acid
Genome, Bacterial
Genomics
Internet
Sequence Alignment
Shigella
User-Computer Interface
Journal Article Research Support, Non-U.S. Gov't

Links to CNCB-NGDC Resources

Database Commons: DBC001567 (ShiBASE)

Word Cloud

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