Geographic potential for outbreaks of Marburg hemorrhagic fever.

A Townsend Peterson, R Ryan Lash, Darin S Carroll, Karl M Johnson
Author Information
  1. A Townsend Peterson: Natural History Museum and Biodiversity Research Center, University of Kansas, Lawrence, Kansas 66047, USA. town@ku.edu

Abstract

Marburg virus represents one of the least well-known of the hemorrhagic fever-causing viruses worldwide; in particular, its geographic potential in Africa remains quite mysterious. Ecologic niche modeling was used to explore the geographic and ecologic potential of Marburg virus in Africa. Model results permitted a reinterpretation of the geographic point of infection in the initiation of the 1975 cases in Zimbabwe, and also anticipated the potential for cases in Angola, where a large outbreak recently (2004-2005) occurred. The geographic potential for additional outbreaks is outlined, including in several countries in which the virus is not known. Overall, results demonstrate that ecologic niche modeling can be a powerful tool in understanding geographic distributions of species and other biologic phenomena such as zoonotic disease transmission from natural reservoir populations.

MeSH Term

Angola
Disease Outbreaks
Ecology
Geography
Humans
Marburg Virus Disease
Marburgvirus
Models, Biological
Risk Factors
Zimbabwe

Word Cloud

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