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Clinical research in cardiology : official journal of the German Cardiac Society
Aug, 2006;95 (8): 429-54.

[Diagnosis and therapy of sepsis].

K Reinhart, F M Brunkhorst, H-G Bone, H Gerlach, M Gründling, G Kreymann, P Kujath, G Marggraf, K Mayer, A Meier-Hellmann, C Peckelsen, C Putensen, F Stüber, M Quintel, M Ragaller, R Rossaint, N Weiler, T Welte, K Werdan
Author Information
  1. K Reinhart: Universitätsklinikum Jena der Friedrich-Schiller-Universität Jena, Klinik für Anästhesiologie und Intensivtherapie, Jena.
PMID: 16868790 DOI: 10.1007/s00392-006-0414-7

Abstract

A recent survey conducted by the publicly funded Competence Network Sepsis (Sep- Net) reveals that severe sepsis and/or septic shock occurs in 75,000 inhabitants (110 out of 100,000) and sepsis in 79,000 inhabitants (116 out of 100,000) in Germany annually. This illness is responsible for approx. 60,000 deaths and ranges as the third most frequent cause of death after acute myocardial infarction. Direct costs for the intensive care of patients with severe sepsis alone amount to approx. 1.77 billion euros, which means that about 30% of the budget in intensive care is used to treat severe sepsis. However, until now German guidelines for the diagnosis and therapy of severe sepsis did not exist. Therefore, the German Sepsis Society initiated the development of guidelines which are based on international recommendations by the International Sepsis Forum (ISF) and the Surviving Sepsis Campaign (SSC) and take into account the structure and organisation of the German health care system. Priority was given to the following guideline topics: a) diagnosis, b) prevention, c) causative therapy, d) supportive therapy, e) adjunctive therapy. The guidelines development process was carefully planned and strictly adhered to according to the requirements of the Working Group of Scientific Medical Societies (AWMF).

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MeSH Term

Critical Care
Germany
Humans
Incidence
Practice Guidelines as Topic
Sepsis
Severity of Illness Index
Treatment Outcome
English Abstract Journal Article Review

Word Cloud

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