Challenges and solutions for recruiting pregnant smokers into a nicotine replacement therapy trial.

Kathryn I Pollak, Cheryl A Oncken, Isaac M Lipkus, Bercedis L Peterson, Geeta K Swamy, Pamela K Pletsch, Pauline Lyna, Rebecca J Namenek Brouwer, Laura J Fish, Evan R Myers
Author Information
  1. Kathryn I Pollak: Duke Comprehensive Cancer Center, Cancer Prevention, Detection and Control Research Program, Department of Community and Family Medicine, Durham, NC 27705, USA. kathryn.pollak@duke.edu

Abstract

Improvements in smoking cessation interventions for pregnant smokers are needed. One major step is to examine the potential effectiveness of nicotine replacement therapy (NRT). The potential benefits of providing pregnant women with NRT to help them quit smoking are still unknown; early interventions to test the effectiveness and efficacy are vital to advancing the field. This paper describes recruitment efforts for a multiclinic trial to test the effectiveness of NRT use in addition to behavioral therapy in promoting cessation during pregnancy. The biggest challenge is recruiting sufficient numbers of pregnant women. This paper discusses specific obstacles for recruitment and solutions. Knowing the potential pitfalls to recruiting pregnant women into these trials can lead to better studies and thus improved outcomes.

Grants

  1. CA100387/NCI NIH HHS
  2. CA68438-06A2/NCI NIH HHS
  3. CA89053/NCI NIH HHS

MeSH Term

Adolescent
Adult
Behavior Therapy
Female
Ganglionic Stimulants
Health Promotion
Humans
Interviews as Topic
Nicotine
Patient Acceptance of Health Care
Patient Selection
Postal Service
Pregnancy
Pregnant Women
Prenatal Care
Randomized Controlled Trials as Topic
Smoking Cessation
Tobacco Use Disorder

Chemicals

Ganglionic Stimulants
Nicotine

Word Cloud

Created with Highcharts 10.0.0pregnantpotentialeffectivenesstherapyNRTwomenrecruitingsmokingcessationinterventionssmokersnicotinereplacementtestpaperrecruitmenttrialsolutionsImprovementsneededOnemajorstepexaminebenefitsprovidinghelpquitstillunknownearlyefficacyvitaladvancingfielddescribeseffortsmulticlinicuseadditionbehavioralpromotingpregnancybiggestchallengesufficientnumbersdiscussesspecificobstaclesKnowingpitfallstrialscanleadbetterstudiesthusimprovedoutcomesChallenges

Similar Articles

Cited By (20)