Human immunodeficiency virus (HIV) antibody avidity testing to identify recent infection in newly diagnosed HIV type 1 (HIV-1)-seropositive persons infected with diverse HIV-1 subtypes.

A Chawla, G Murphy, C Donnelly, C L Booth, M Johnson, J V Parry, A Phillips, A M Geretti
Author Information
  1. A Chawla: Department of Virology, Royal Free Hospital, Royal Free and University College Medical School, London, UK.

Abstract

A guanidine-based antibody avidity assay for the identification of recently acquired human immunodeficiency virus type 1 (HIV-1) infection was evaluated. The kinetics of maturation of antibody avidity were determined prospectively in 23 persons undergoing acute seroconversion followed for up to 1,075 days. Avidity indices (AI) of

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MeSH Term

Adult
Aged
Antibody Affinity
Female
Guanidine
HIV Antibodies
HIV Infections
HIV Seropositivity
HIV-1
Humans
Kinetics
Male
Middle Aged
Multivariate Analysis

Chemicals

HIV Antibodies
Guanidine

Word Cloud

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