Studies on the synthesis of durhamycin A: stereoselective synthesis of a model aglycone.

Rajan Pragani, William R Roush
Author Information
  1. Rajan Pragani: Department of Chemistry, Scripps Florida, Jupiter, Florida 33458, USA.

Abstract

A stereoselective synthesis of the model aglycone corresponding to the anti-HIV aureolic acids durhamycins A (1) and B (2) is described.

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Grants

  1. R01 GM038436/NIGMS NIH HHS
  2. R01 GM038436-22/NIGMS NIH HHS
  3. GM038436/NIGMS NIH HHS

MeSH Term

Aldehydes
Alkadienes
Fatty Alcohols
Molecular Structure
Plicamycin
Stereoisomerism
Temperature

Chemicals

Aldehydes
Alkadienes
Fatty Alcohols
durhamycin A
propadiene
acyloin
Plicamycin

Word Cloud

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