Real-time PCR and enrichment culture for sensitive detection and enumeration of Escherichia coli.

Hajime Takahashi, Bon Kimura, Yuichiro Tanaka, Junko Shinozaki, Takayuki Suda, Tateo Fujii
Author Information
  1. Hajime Takahashi: Department of Food Science and Technology, Faculty of Marine Science, Tokyo University of Marine Science and Technology, 5-7 Konan 4, Minato, Tokyo 108-8477, Japan.

Abstract

Rapid enumeration of Escherichia coli strains by quantitative real-time PCR targeting the uidA gene was developed and confirmed for minced beef, tuna and raw oyster. Higher sensitivity (1 CFU/g of E. coli in all three food samples) was obtained by incubating for 7 h in TSB. Colony-directed E. coli specific TaqMan PCR assay could effectively distinguish colonies grown on various selective media within 1.5-h. Inspection of E. coli in food testing laboratories is important, and our rapid E. coli detection strategy will contribute to quality control in food industries.

MeSH Term

Animals
Colony Count, Microbial
DNA, Bacterial
Escherichia coli
Escherichia coli Proteins
Food Microbiology
Humans
Polymerase Chain Reaction
Sensitivity and Specificity
Time Factors

Chemicals

DNA, Bacterial
Escherichia coli Proteins

Word Cloud

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