The mucosal firewalls against commensal intestinal microbes.
Andrew J Macpherson, Emma Slack, Markus B Geuking, Kathy D McCoy
Author Information
Andrew J Macpherson: DKF, Maurice Müller Laboratories, Department of Visceral Surgery and Medicine, University of Bern, Room G801, Bern, Switzerland. andrew.macpherson@insel.ch
Mammals coexist with an extremely dense microbiota in the lower intestine. Despite the constant challenge of small numbers of microbes penetrating the intestinal surface epithelium, it is very unusual for these organisms to cause disease. In this review article, we present the different mucosal firewalls that contain and allow mutualism with the intestinal microbiota.
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Animals
Host-Pathogen Interactions
Humans
Intestinal Diseases
Intestinal Mucosa
