Herbal excipients in novel drug delivery systems.

A Shirwaikar, Annie Shirwaikar, S Lakshmana Prabu, G Aravind Kumar
Author Information

Abstract

The use of natural excipients to deliver the bioactive agents has been hampered by the synthetic materials. However advantages offered by these natural excipients are their being non-toxic, less expensive and freely available. The performance of the excipients partly determines the quality of the medicines. The traditional concept of the excipients as any component other than the active substance has undergone a substantial evolution from an inert and cheap vehicle to an essential constituent of the formulation. Excipients are any component other than the active substance(s) intentionally added to formulation of a dosage form. This article gives an overview of herbal excipients which are used in conventional dosage forms as well as novel drug delivery systems.

Keywords

References

  1. Eur J Pharm Sci. 1999 Oct;9(1):1-7 [PMID: 10493990]
  2. Drug Dev Ind Pharm. 2000 Oct;26(10):1025-38 [PMID: 11028217]
  3. J Control Release. 2003 Sep 4;91(3):345-54 [PMID: 12932712]
  4. Drug Dev Ind Pharm. 2004 May;30(5):491-5 [PMID: 15244084]
  5. J Pharm Sci. 1994 May;83(5):632-5 [PMID: 8071810]
  6. Int J Pharm. 2005 Jan 31;289(1-2):167-78 [PMID: 15652209]
  7. Drug Deliv. 2005 May-Jun;12(3):149-57 [PMID: 16025844]
  8. Drug Dev Ind Pharm. 2004 Apr;30(4):359-67 [PMID: 15132178]
  9. Int J Pharm. 2005 May 30;296(1-2):1-11 [PMID: 15885450]
  10. J Control Release. 2002 Oct 4;83(2):231-9 [PMID: 12363449]
  11. Int J Pharm. 2002 Jul 25;241(2):353-66 [PMID: 12100863]
  12. Ren Fail. 2003 Jul;25(4):525-34 [PMID: 12911156]
  13. J Control Release. 2003 Oct 30;92(3):375-82 [PMID: 14568418]
  14. Drug Deliv. 2006 Jan-Feb;13(1):69-77 [PMID: 16401596]
  15. Skin Pharmacol Physiol. 2005 Nov-Dec;18(6):263-72 [PMID: 16113596]
  16. Biomaterials. 2004 Aug;25(18):4355-62 [PMID: 15046926]
  17. Int J Pharm. 2000 Aug 10;203(1-2):179-92 [PMID: 10967440]
  18. J Control Release. 2005 Aug 18;106(1-2):111-22 [PMID: 15993975]
  19. Ophthalmologe. 2004 May;101(5):496-9 [PMID: 15138798]
  20. Drug Dev Ind Pharm. 1999 May;25(5):651-7 [PMID: 10219535]
  21. Int J Pharm. 2004 Jan 9;269(1):169-76 [PMID: 14698588]
  22. AAPS PharmSciTech. 2005 Jul 14;6(1):E14-21 [PMID: 16353958]
  23. Drug Deliv. 2003 Jan-Mar;10(1):21-8 [PMID: 12554360]
  24. Int J Pharm. 1999 Nov 5;189(2):171-8 [PMID: 10536245]
  25. Int J Pharm. 2001 Aug 14;224(1-2):19-38 [PMID: 11472812]
  26. J Microencapsul. 2005 Jun;22(4):343-51 [PMID: 16214783]
  27. Boll Chim Farm. 2002 Jan-Feb;141(1):21-8 [PMID: 12064053]
  28. Curr Drug Deliv. 2004 Apr;1(2):93-102 [PMID: 16305374]
  29. Int J Pharm. 1997 Nov 28;157(2):181-187 [PMID: 10477815]
  30. AAPS PharmSciTech. 2005 Dec 07;6(4):E626-32 [PMID: 16408864]
  31. Drug Dev Ind Pharm. 2004 Jul;30(6):609-17 [PMID: 15285334]
  32. Int J Pharm. 2005 Sep 14;301(1-2):268-76 [PMID: 16023808]
  33. Curr Drug Deliv. 2005 Apr;2(2):155-63 [PMID: 16305416]
  34. Drug Dev Ind Pharm. 1999 Dec;25(12):1271-6 [PMID: 10612023]
  35. Int J Pharm. 2005 May 13;295(1-2):15-27 [PMID: 15898143]
  36. Eur J Pharm Biopharm. 2002 Jul;54(1):95-9 [PMID: 12084508]
  37. Drug Dev Ind Pharm. 2002 Jul;28(6):621-30 [PMID: 12149954]

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