- Benjamin B Kaufmann: Infectious Disease Initiative, The Broad Institute, Cambridge, MA 02141, USA; Massachusetts General Hospital, Boston, MA 02114, USA.
In this issue of Molecular Cell, Kohanski et al. (2010) demonstrate that even subinhibitory concentrations of bactericidal antibiotics result in the generation of reactive oxygen species, leading to an increase in mutation rate and the emergence of multidrug-resistant bacterial strains.