Evaluation of DNA intramolecular interactions for nucleosome positioning in yeast.

Michael Fernandez, Satoshi Fujii, Hidetoshi Kono, Akinori Sarai
Author Information
  1. Michael Fernandez: Department of Bioscience and Bioinformatics, Kyushu Institute of Technology (KIT), Iizuka 820-8502, Japan. re0701m@bio.kyutech.ac.jp

Abstract

We calculated intramolecular interaction energies of DNA by threading DNA sequences around crystal structures of nucleosomes. The strength of the intramolecular energy oscillations at frequency approximately 10 bps for dinucleotides was in agreement with previous nucleosome models. The intramolecular energy calculated along yeast genome positively correlated with nucleosome positioning experimentally measured.

MeSH Term

DNA, Fungal
Nucleosomes
Saccharomyces cerevisiae

Chemicals

DNA, Fungal
Nucleosomes

Word Cloud

Created with Highcharts 10.0.0intramolecularDNAnucleosomecalculatedenergyyeastpositioninginteractionenergiesthreadingsequencesaroundcrystalstructuresnucleosomesstrengthoscillationsfrequencyapproximately10bpsdinucleotidesagreementpreviousmodelsalonggenomepositivelycorrelatedexperimentallymeasuredEvaluationinteractions

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