Epigenetic marks identify functional elements.

Randall H Morse
Author Information

Abstract

Enhancers and transcription factor binding sites that control cell-specific transcription in higher eukaryotes can be found up to hundreds of kilobases from the promoters that they control, making their identification challenging. A new study uses a model based on histone modifications and chromatin dynamics to predict functional elements involved in androgen receptor response.

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MeSH Term

Chromatin
Enhancer Elements, Genetic
Gene Expression Regulation
Humans
Models, Genetic
Receptors, Androgen
Regulatory Elements, Transcriptional
Transcription Factors

Chemicals

Chromatin
Receptors, Androgen
Transcription Factors

Word Cloud

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