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Journal of clinical and experimental neuropsychology
Jan, 2011;33 (1): 9-16.

Gender differences in neuropsychological performance in individuals with atherosclerosis: impact of vascular function.

Caitlin S Moore, Ivy N Miller, Renee L Andersen, Stephan Arndt, William G Haynes, David J Moser
Author Information
  1. Caitlin S Moore: Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
PMID: 20512721 DOI: 10.1080/13803391003757841

Abstract

This study was conducted to assess gender differences in cognition in elderly individuals (N = 88; 38 women, 50 men) with atherosclerotic vascular disease (AVD) and to determine whether these were attributable to differences in vascular health. Assessments included neuropsychological testing and measurement of forearm vascular function using venous occlusion plethysmography. There was a significant female advantage on multiple neuropsychological tests. This gender effect was reduced somewhat but remained significant when controlling for education and vascular function. Our study suggests that gender differences in cognition persist into older age and are not primarily due to gender differences in vascular health.

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Grants

  1. R01 AG030417/NIA NIH HHS
  2. P01 HL014388/NHLBI NIH HHS
  3. K23 AG020649/NIA NIH HHS
  4. R01 AG030417-03/NIA NIH HHS
  5. UL1 RR024979/NCRR NIH HHS

MeSH Term

Acetylcholine
Aged
Aged, 80 and over
Atherosclerosis
Blood Pressure
Blood Vessels
Cognition Disorders
Female
Heart Rate
Humans
Male
Middle Aged
Neuropsychological Tests
Plethysmography
Sex Factors
Vasodilator Agents
Verapamil

Chemicals

Vasodilator Agents
Verapamil
Acetylcholine
Journal Article

Word Cloud

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