Micelle to fibre biocatalytic supramolecular transformation of an aromatic peptide amphiphile.

Jan W Sadownik, Joy Leckie, Rein V Ulijn
Author Information
  1. Jan W Sadownik: WestCHEM, University of Strathclyde, Department of Pure and Applied Chemistry, Thomas Graham Building, 295 Cathedral Street, Glasgow, UK G1 1XL.

Abstract

We use a range of spectroscopic methods to provide mechanistic insight into a phosphatase-driven supramolecular transformation whereby an amphiphilic peptide building block, upon dephosphorylation, switches from a solution-phase, micellar structure to a gel-phase, chiral uni-directional nanofibre morphology.

MeSH Term

Biocatalysis
Micelles
Nanofibers
Peptides
Phosphorylation
Pyrenes
Spectrometry, Fluorescence

Chemicals

Micelles
Peptides
Pyrenes
pyrene

Word Cloud

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