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Musculoskeletal surgery
Aug, 2011;95 (2): 59-67.

Metabolic myopathies: functional evaluation by different exercise testing approaches.

L Volpi, G Ricci, D Orsucci, R Alessi, F Bertolucci, S Piazza, C Simoncini, M Mancuso, G Siciliano
Author Information
  1. L Volpi: Department of Neuroscience, Neurological Clinic, University of Pisa, Via Roma 67, 56126 Pisa, Italy.
PMID: 21373907 DOI: 10.1007/s12306-011-0096-9

Abstract

Metabolic myopathies are a clinically and etiologically heterogeneous group of disorders due to defects in muscular energy metabolism. They include glycogen storage diseases, fatty acid oxidation defects, and mitochondrial disorders. The typical manifestations of a metabolic myopathy are exercise-induced myalgias, exercise intolerance, and cramps. Evaluating subjects with such symptoms is not easy because of the frequent lack of clinical features. Exercise tests are, therefore, reliable screening tools. Here, we discuss the possible role of such exercise testing techniques in the diagnostic approach of a patient with suspected metabolic myopathy.

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MeSH Term

Algorithms
Exercise
Exercise Test
Forearm
Glycogen Storage Disease
Humans
Lipid Metabolism Disorders
Metabolic Diseases
Mitochondrial Diseases
Muscular Diseases
Predictive Value of Tests
Sensitivity and Specificity
Journal Article Research Support, Non-U.S. Gov't Review

Word Cloud

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