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Journal of plant research
Jul, 2011;124 (4): 539-48.

Systems biology approaches to abscisic acid signaling.

Taishi Umezawa
Author Information
  1. Taishi Umezawa: Gene Discovery Research Group, RIKEN Plant Science Center, 3-1-1 Kouyadai, Tsukuba, Ibaraki 305-0074, Japan. umezawa@rtc.riken.jp
PMID: 21461660 DOI: 10.1007/s10265-011-0418-x

Abstract

Recent advances in our understanding of abscisic acid (ABA) signaling have identified a core pathway consisting of receptors (PYR/PYL/RCAR), protein phosphatases (PP2C), protein kinases (SnRK2), and several downstream factors that will lead to the next stage of ABA research. Systems biology will be an important concept for further understanding ABA responses in plants. In this review, two practical approaches of systems biology to ABA signaling are presented: the one is 'transcriptome analysis', which covers coding genes as well as unannotated transcripts, and the other is 'phosphoproteomics'. The latter technology will offer an unprecedented overview of the regulatory networks involved in ABA signaling because protein phosphorylation/dephosphorylation is a major center of such regulation. Systematic studies will contribute to our understanding of the network structure and dynamics of ABA signaling; moreover, systems biology will facilitate ABA signaling studies as well as future biotechnological applications in crops or trees.

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MeSH Term

Abscisic Acid
GTP-Binding Proteins
Gene Expression Profiling
Gene Expression Regulation, Plant
Phosphoprotein Phosphatases
Phosphorylation
Plant Growth Regulators
Plant Proteins
Plant Stomata
Plants
Protein Serine-Threonine Kinases
Proteomics
Signal Transduction
Systems Biology
Transcription Factors

Chemicals

Plant Growth Regulators
Plant Proteins
Transcription Factors
Abscisic Acid
Protein Serine-Threonine Kinases
Phosphoprotein Phosphatases
GTP-Binding Proteins
Journal Article Research Support, Non-U.S. Gov't Review

Word Cloud

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