Extensive systemic sarcoidosis with testicular involvement mimicking metastatic testicular cancer.

Yun Beom Kim, Yeun Goo Chung, Sang Jin Kim, Se Joong Kim, Hyun Soo Ahn, Hee Jae Joo, Sun Il Kim
Author Information
  1. Yun Beom Kim: Department of Urology, Seoul Veterans Hospital, Seoul, Korea.

Abstract

Sarcoidosis is an idiopathic, multisystem disease that rarely involves the genitourinary tract. Here we present an unusual case of testicular sarcoidosis with extensive lymphadenopathy that mimicked a metastatic testicular tumor. A 27-year-old male presented with a palpable right testicular mass accompanied by multiple palpable inguinal lymph nodes. The scrotal ultrasound showed a hypoechoic lesion at the inferior portion of the right testis. Extensive enlarged lymph nodes were noted in multiple areas on the abdominal computed tomography. Preoperative testicular tumor markers were within the normal range. Exploration of the right testis with a frozen section analysis of the right testicular mass and of a palpable right inguinal lymph node showed granulomatous inflammation. The testis was salvaged and the final pathological diagnosis was sarcoidosis. Treatment with high-dose corticosteroids resulted in complete resolution of the intratesticular mass and a significant decrease in the extent of the lymphadenopathy.

Keywords

References

  1. Urology. 2006 Jan;67(1):200 [PMID: 16413374]
  2. Urology. 1985 Sep;26(3):288-9 [PMID: 4035845]
  3. Intern Med. 1996 Jul;35(7):579-82 [PMID: 8842767]
  4. J Urol. 2008 Mar;179(3):1147 [PMID: 18206954]
  5. Cancer. 1998 Jul 15;83(2):337-43 [PMID: 9669817]
  6. Nat Clin Pract Urol. 2007 Apr;4(4):227-30 [PMID: 17415355]
  7. Int J Urol. 2004 May;11(5):345-8 [PMID: 15147556]
  8. J Urol. 1977 Sep;118(3):487-8 [PMID: 904069]

Word Cloud

Created with Highcharts 10.0.0testicularrightsarcoidosispalpablemasslymphtestisSarcoidosislymphadenopathymetastatictumormultipleinguinalnodesshowedExtensiveidiopathicmultisystemdiseaserarelyinvolvesgenitourinarytractpresentunusualcaseextensivemimicked27-year-oldmalepresentedaccompaniedscrotalultrasoundhypoechoiclesioninferiorportionenlargednotedareasabdominalcomputedtomographyPreoperativemarkerswithinnormalrangeExplorationfrozensectionanalysisnodegranulomatousinflammationsalvagedfinalpathologicaldiagnosisTreatmenthigh-dosecorticosteroidsresultedcompleteresolutionintratesticularsignificantdecreaseextentsystemicinvolvementmimickingcancerLymphaticdiseasesSteroidsTesticularneoplasmsTestis

Similar Articles

Cited By