Cognitive predictors of everyday functioning in older adults: results from the ACTIVE Cognitive Intervention Trial.

Alden L Gross, George W Rebok, Frederick W Unverzagt, Sherry L Willis, Jason Brandt
Author Information
  1. Alden L Gross: Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, 798 Hampton House, 624 N. Broadway, Baltimore, MD 21205, USA. aldengross@hsl.harvard.edu

Abstract

OBJECTIVE: The present study sought to predict changes in everyday functioning using cognitive tests.
METHODS: Data from the Advanced Cognitive Training for Independent and Vital Elderly trial were used to examine the extent to which competence in different cognitive domains--memory, inductive reasoning, processing speed, and global mental status--predicts prospectively measured everyday functioning among older adults. Coefficients of determination for baseline levels and trajectories of everyday functioning were estimated using parallel process latent growth models.
RESULTS: Each cognitive domain independently predicts a significant proportion of the variance in baseline and trajectory change of everyday functioning, with inductive reasoning explaining the most variance (R2 = .175) in baseline functioning and memory explaining the most variance (R2 = .057) in changes in everyday functioning.
DISCUSSION: Inductive reasoning is an important determinant of current everyday functioning in community-dwelling older adults, suggesting that successful performance in daily tasks is critically dependent on executive cognitive function. On the other hand, baseline memory function is more important in determining change over time in everyday functioning, suggesting that some participants with low baseline memory function may reflect a subgroup with incipient progressive neurologic disease.

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Grants

  1. U01 NR04508/NINR NIH HHS
  2. U01AG14276/NIA NIH HHS
  3. U01AG14260/NIA NIH HHS
  4. U01AG14263/NIA NIH HHS
  5. U01 AG014263/NIA NIH HHS
  6. U01AG14282/NIA NIH HHS
  7. R37 AG024102/NIA NIH HHS
  8. U01 AG14289/NIA NIH HHS
  9. U01NR04507/NINR NIH HHS

MeSH Term

Activities of Daily Living
Aged
Cognition Disorders
Executive Function
Female
Follow-Up Studies
Humans
Male
Mental Recall
Mental Status Schedule
Models, Psychological
Problem Solving
Psychometrics
Reaction Time
Reproducibility of Results

Word Cloud

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