Cognitive function in morbidly obese individuals with and without binge eating disorder.

Rachel Galioto, Mary Beth Spitznagel, Gladys Strain, Michael Devlin, Ronald Cohen, Robert Paul, Ross D Crosby, James E Mitchell, John Gunstad
Author Information
  1. Rachel Galioto: Kent State University, Kent, OH 44242, USA.

Abstract

OBJECTIVE: Obesity is associated with poorer cognitive function and impulsivity, which may contribute to binge eating disorder (BED). The objective of this study was to compare cognitive function in morbidly obese individuals with and without BED.
METHOD: A total of 131 morbidly obese individuals (41 with past or present BED, 90 with no BED history) completed a computerized battery of cognitive tests including executive, memory, language, and attention.
RESULTS: Both groups of participants evidenced high rates of cognitive impairment; however, no significant differences emerged between persons with and without BED on cognitive testing. Comparison of persons without BED, current BED, and past BED also yielded no differences.
DISCUSSION: In the present sample, morbidly obese individuals with and without BED were clinically indistinguishable on tests of cognitive function. Our findings suggest that obesity, rather than binge eating, may be more directly related to cognition. Future studies should further examine this relationship because it might provide greater insight into the neural mechanisms for this BED.

References

  1. Int J Eat Disord. 2005 Nov;38(3):244-51 [PMID: 16211626]
  2. Braz J Psychiatry. 2010 Dec;32(4):381-8 [PMID: 21308259]
  3. Surg Obes Relat Dis. 2011 Jul-Aug;7(4):465-72 [PMID: 21145295]
  4. J Am Geriatr Soc. 2010 Aug;58(8):1427-32 [PMID: 20646100]
  5. Obesity (Silver Spring). 2010 Oct;18(10):1938-43 [PMID: 20168309]
  6. Ther Umsch. 2006 Aug;63(8):529-33 [PMID: 16941397]
  7. Arch Clin Neuropsychol. 2007 Feb;22(2):261-70 [PMID: 17443924]
  8. Compr Psychiatry. 2007 Mar-Apr;48(2):124-31 [PMID: 17292702]
  9. Obesity (Silver Spring). 2010 Mar;18(3):499-504 [PMID: 19713949]
  10. Eat Weight Disord. 2007 Dec;12(4):e78-82 [PMID: 18227630]
  11. Arch Intern Med. 2007 Jul 9;167(13):1420-7 [PMID: 17620537]
  12. Int J Eat Disord. 2007 Dec;40(8):727-32 [PMID: 17683093]
  13. Neurology. 1995 Jul;45(7):1253-60 [PMID: 7617178]
  14. Neuroimage. 2011 Jun 1;56(3):1749-57 [PMID: 21419229]
  15. Int J Eat Disord. 2009 Apr;42(3):228-34 [PMID: 18951458]
  16. J Clin Exp Neuropsychol. 2010 Apr;32(4):358-65 [PMID: 19856232]
  17. Appetite. 2004 Dec;43(3):303-7 [PMID: 15527933]
  18. Int J Eat Disord. 2007 Nov;40 Suppl:S123-9 [PMID: 17685383]

Grants

  1. HL089311/NHLBI NIH HHS
  2. DK075119/NIDDK NIH HHS
  3. R56 DK075119-05A1/NIDDK NIH HHS
  4. R01 HL089311-04/NHLBI NIH HHS
  5. R56 DK075119/NIDDK NIH HHS
  6. R01 DK075119-04/NIDDK NIH HHS
  7. R01 HL089311/NHLBI NIH HHS
  8. R01 DK075119/NIDDK NIH HHS

MeSH Term

Adult
Aged
Attention
Binge-Eating Disorder
Cognition Disorders
Comorbidity
Cross-Sectional Studies
Executive Function
Female
Humans
Impulsive Behavior
Language
Male
Memory
Middle Aged
Multivariate Analysis
Neuropsychological Tests
Obesity, Morbid
Prevalence
United States

Word Cloud

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