Contrasting case definitions for chronic fatigue syndrome, Myalgic Encephalomyelitis/chronic fatigue syndrome and myalgic encephalomyelitis.

Leonard A Jason, Abigail Brown, Erin Clyne, Lindsey Bartgis, Meredyth Evans, Molly Brown
Author Information
  1. Leonard A Jason: DePaul University, Chicago, IL 60614, USA.

Abstract

This article uses data from patients recruited using the 1994 case definition of chronic fatigue syndrome (CFS) to contrast those meeting criteria for the Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS) Canadian case definition with those that did not meet these criteria. The study also contrasts those meeting criteria for Myalgic Encephalomyelitis (ME) based on criteria from Ramsay and other theorists with those that did not meet the ME criteria. The ME/CFS case definition criteria identified a subset of patients with more functional impairments and physical, mental, and cognitive problems than the subset not meeting these criteria. The ME subset had more functional impairments, and more severe physical and cognitive symptoms than the subset not meeting ME criteria. When applied to a population meeting the 1994 CFS case definition, both ME/CFS and ME criteria appear to select a more severe subset of patients.

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Grants

  1. R01 AI049720/NIAID NIH HHS
  2. A149720/PHS HHS
  3. A136295/PHS HHS

MeSH Term

Adaptation, Psychological
Adult
Analysis of Variance
Cognition
Fatigue Syndrome, Chronic
Female
Health Status Indicators
Humans
Male
Mental Health
Psychometrics
Severity of Illness Index
Stress, Psychological
Surveys and Questionnaires

Word Cloud

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