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Science (New York, N.Y.)
Dec 09, 2011;334 (6061): 1413-5.

Perceptual learning incepted by decoded fMRI neurofeedback without stimulus presentation.

Kazuhisa Shibata, Takeo Watanabe, Yuka Sasaki, Mitsuo Kawato
Author Information
  1. Kazuhisa Shibata: Advanced Telecommunications Research Institute International Computational Neuroscience Laboratories, Keihanna Science City, Kyoto 619-0288, Japan.
PMID: 22158821 DOI: 10.1126/science.1212003

Abstract

It is controversial whether the adult primate early visual cortex is sufficiently plastic to cause visual perceptual learning (VPL). The controversy occurs partially because most VPL studies have examined correlations between behavioral and neural activity changes rather than cause-and-effect relationships. With an online-feedback method that uses decoded functional magnetic resonance imaging (fMRI) signals, we induced activity patterns only in early visual cortex corresponding to an orientation without stimulus presentation or participants' awareness of what was to be learned. The induced activation caused VPL specific to the orientation. These results suggest that early visual areas are so plastic that mere inductions of activity patterns are sufficient to cause VPL. This technique can induce plasticity in a highly selective manner, potentially leading to powerful training and rehabilitative protocols.

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Grants

  1. R01 MH091801/NIMH NIH HHS
  2. R01 EY015980-06/NEI NIH HHS
  3. R01 EY015980-07/NEI NIH HHS
  4. R01 EY015980-04A2/NEI NIH HHS
  5. R01 EY015980-08/NEI NIH HHS
  6. R01 EY015980-05/NEI NIH HHS
  7. R01 EY015980/NEI NIH HHS
  8. R01 AG031941/NIA NIH HHS
  9. R01 AG031941-04/NIA NIH HHS

MeSH Term

Adult
Analysis of Variance
Brain Mapping
Female
Humans
Learning
Magnetic Resonance Imaging
Male
Neurofeedback
Neuronal Plasticity
Size Perception
Visual Cortex
Visual Perception
Young Adult
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.
Article has an altmetric score of 235

Word Cloud

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