2-(1H-Benzotriazol-1-yl)-1-(furan-2-yl)ethanol.

Ozden Ozel Güven, Meral Bayraktar, Simon J Coles, Tuncer Hökelek
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Abstract

In the title compound, C(12)H(11)N(3)O(2), the benzotriazole ring system is approximately planar [maximum deviation = 0.008 (1) Å] and its mean plane is oriented at a dihedral angle of 24.05 (4)° with respect to the furan ring. In the crystal, O-H⋯N hydrogen bonds link the mol-ecules into chains along the ac diagonal. π-π stacking between the furan rings, between the triazole and benzene rings, and between the benzene rings [centroid-centroid distances = 3.724 (1), 3.786 (1) and 3.8623 (9) Å] are also observed.

References

  1. Bioorg Med Chem Lett. 1998 Aug 4;8(15):1973-8 [PMID: 9873469]
  2. J Pharm Sci. 2004 Mar;93(3):601-11 [PMID: 14762899]
  3. Acta Crystallogr Sect E Struct Rep Online. 2008 Jun 13;64(Pt 7):o1254 [PMID: 21202888]
  4. Acta Crystallogr D Biol Crystallogr. 2009 Feb;65(Pt 2):148-55 [PMID: 19171970]
  5. Acta Crystallogr Sect E Struct Rep Online. 2010 Mar 27;66(Pt 4):o959 [PMID: 21580762]
  6. Org Lett. 2001 Sep 6;3(18):2807-9 [PMID: 11529762]
  7. Bioorg Med Chem. 2004 May 15;12(10):2617-24 [PMID: 15110843]
  8. Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22 [PMID: 18156677]
  9. Bioorg Med Chem Lett. 2006 Feb 15;16(4):999-1004 [PMID: 16298529]
  10. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2141-4 [PMID: 12798322]
  11. Acta Crystallogr Sect E Struct Rep Online. 2011 Sep 1;67(Pt 9):o2510 [PMID: 22064838]

Word Cloud

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