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Therapeutic advances in musculoskeletal disease
Apr, 2009;1 (2): 87-96.

Advancing our understanding of osteocyte cell biology.

Dayong Guo, Lynda F Bonewald
Author Information
  1. Dayong Guo: University of Missouri, Kansas City, MO, USA.
PMID: 22870430 DOI: 10.1177/1759720X09341484

Abstract

Osteocytes were the forgotten bone cell until the bone community could become convinced that these cells do serve an important role in bone function and maintenance. In this review we trace the history of osteocyte characterization and present some of the major observations that are leading to the conclusion that these cells are not passive placeholders residing in the bone matrix, but are indeed, major orchestrators of bone remodeling.

Keywords

bone remodelling osteocytes parathyroid hormone

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Grants

  1. P01 AR046798/NIAMS NIH HHS
Journal Article
Article has an altmetric score of 3

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Created with Highcharts 10.0.0bonecellcellsosteocytemajorOsteocytesforgottencommunitybecomeconvincedserveimportantrolefunctionmaintenancereviewtracehistorycharacterizationpresentobservationsleadingconclusionpassiveplaceholdersresidingmatrixindeedorchestratorsremodelingAdvancingunderstandingbiologyremodellingosteocytesparathyroidhormone

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