Immunomicelles for advancing personalized therapy.

Rupa R Sawant, Aditi M Jhaveri, Vladimir P Torchilin
Author Information
  1. Rupa R Sawant: Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, Boston, MA 02115, USA.

Abstract

Personalized medicine, which ultimately seeks to afford tailored therapeutic regimens for individual patients, is quickly emerging as a new paradigm in the diagnosis and treatment of diseases. The idea of casting aside generic treatments in favor of patient-centric therapies has become feasible owing to advances in nanotechnology and drug delivery coupled with an enhanced knowledge of genomics and an understanding of disease at the molecular level. This review highlights polymeric immunomicelles as a class of nanocarriers that have the potential to combine diagnosis, targeted drug therapy, as well as imaging and monitoring of therapeutic response, to render a personalized approach to the management of disease. Smart multi-functional immunomicelles, as the next generation of nanocarriers, are poised for facilitating personalized cancer treatment. This review provides an assessment of immunomicelles as tools for advancing personalized therapy of diseases, with cancer being the major focus.

MeSH Term

Animals
Antineoplastic Agents
Drug Carriers
Humans
Micelles
Nanomedicine
Neoplasms
Plaque, Atherosclerotic
Polymers
Precision Medicine
RNA, Small Interfering

Chemicals

Antineoplastic Agents
Drug Carriers
Micelles
Polymers
RNA, Small Interfering

Word Cloud

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