The first Vietnamese patient with fulminant type 1 diabetes mellitus.

Hee Jin Kim, Ho-Su Kim, Jong Ryeal Hahm, Jung Hwa Jung, Soo Kyoung Kim, Sang Min Lee, Sungsu Kim, Soon Il Chung, Tae Sik Jung
Author Information
  1. Hee Jin Kim: Department of Internal Medicine, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine, South Korea.

Abstract

A 23-year-old pregnant woman had a stillbirth at 30 weeks gestation due to abrupt diabetic ketoacidosis. The patient had a normal HbA1c, severe hyperglycemia, negative islet cell autoantibodies, and very low insulin secretion capacity. The viral markers associated with fulminant type 1 diabetes were negative. The patient's human leukocyte antigen genotypes were DRB1**04:06 and DQB1*03:01/05:02, not common subtypes for fulminant type 1 diabetes. This is the first Vietnamese patient with fulminant type 1 diabetes mellitus.

MeSH Term

Asian People
Diabetes Mellitus, Type 1
Diabetic Ketoacidosis
Female
HLA-DQ beta-Chains
HLA-DRB1 Chains
Humans
Pregnancy
Pregnancy Complications
Stillbirth
Young Adult

Chemicals

HLA-DQ beta-Chains
HLA-DQB1 antigen
HLA-DRB1 Chains
HLA-DRB1*04:06 antigen

Word Cloud

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