Development and implementation of a computerized system for collection, processing, and administration of cellular therapy products.

Laura C Gatzos, Susan Barbetti, Suzanne Bas-Davis, Albert Mailman, Philip Brzezinski, Paul Ruseau, Holly Barr Vermilya, Darlys Schott, Edna Marston, Olive J Sturtevant, Jerome Ritz, Lawrence N Shulman
Author Information
  1. Laura C Gatzos: Partners Healthcare Information Services, Charlestown, MA 02129-2000, USA. lgatzos@partners.org

Abstract

Great strides have been made in computerization of ordering processes for general medications and chemotherapy agents. However, systems for ordering, processing, and administration of cellular therapies continue to be largely paper-based, without the safety features of computerized order entry. To address this deficit, Partners Healthcare System Information Services (PHS-IS; Boston, MA) has worked with oncologists and staff in the cell processing laboratory at the Dana-Farber Cancer Institute (Boston, MA) to develop and implement a novel, comprehensive computerized system for physician ordering and management of cellular products. A multidisciplinary team was formed to accomplish the task of developing a cellular product management system. This team identified the unique characteristics of cellular therapies and sought to develop a comprehensive computerized system that addressed these needs. The biotherapy order entry system developed and implemented by PHS-IS includes a suite of three interrelated applications that addresses all requirements of a traditional computerized provider order entry system, as well as features unique to cellular therapies. The biotherapy suite of applications has addressed patient safety concerns, streamlined the ordering of cellular therapy products, and has reduced opportunities for error and delay in product administration.

References

  1. Clin Cancer Res. 2011 Aug 15;17(16):5233-8 [PMID: 21700764]
  2. Semin Oncol Nurs. 2009 May;25(2):95-9 [PMID: 19411011]
  3. J Oncol Pract. 2011 Jul;7(4):226-30 [PMID: 22043185]
  4. Transfusion. 2011 Apr;51(4):799-807 [PMID: 20880003]
  5. Cancer. 2005 Dec 1;104(11):2477-83 [PMID: 16245353]
  6. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15825-30 [PMID: 19717467]
  7. Transfusion. 2011 Jan;51(1):137-47 [PMID: 20609197]
  8. J Oncol Pract. 2008 Sep;4(5):254-257 [PMID: 29452528]
  9. Biol Blood Marrow Transplant. 2011 Aug;17(8):1196-204 [PMID: 21193054]
  10. Transfusion. 2010 Dec;50(12):2670-5 [PMID: 21126251]
  11. Bone Marrow Transplant. 2011 May;46(5):659-67 [PMID: 20697368]
  12. Nat Rev Mol Cell Biol. 2011 Feb;12(2):126-31 [PMID: 21253000]
  13. Clin Cancer Res. 2011 Jul 1;17(13):4550-7 [PMID: 21498393]
  14. N Engl J Med. 2010 Nov 25;363(22):2091-101 [PMID: 21105791]
  15. Nature. 2011 Dec 21;480(7378):480-9 [PMID: 22193102]
  16. J Clin Oncol. 2003 Sep 1;21(17):3343-50 [PMID: 12947071]
  17. J Oncol Pract. 2008 Jul;4(4):203-206 [PMID: 29447501]
  18. Clin Cancer Res. 2011 Jun 1;17(11):3520-6 [PMID: 21471425]
  19. J Oncol Pract. 2011 Jul;7(4):233-7 [PMID: 22043187]
  20. Circ Res. 2011 Sep 30;109(8):923-40 [PMID: 21960725]
  21. Nat Rev Clin Oncol. 2011 Aug 02;8(10):577-85 [PMID: 21808266]

MeSH Term

Biological Therapy
Cell Transplantation
Drug Therapy, Computer-Assisted
Humans
Infant
Leukemia
Medical Order Entry Systems
Medical Records Systems, Computerized
Medication Errors
Tissue Transplantation

Word Cloud

Created with Highcharts 10.0.0cellularsystemcomputerizedorderingprocessingadministrationtherapiesorderentryproductssafetyfeaturesPHS-ISBostonMAdevelopcomprehensivemanagementteamproductuniqueaddressedbiotherapysuiteapplicationstherapyGreatstridesmadecomputerizationprocessesgeneralmedicationschemotherapyagentsHoweversystemscontinuelargelypaper-basedwithoutaddressdeficitPartnersHealthcareSystemInformationServicesworkedoncologistsstaffcelllaboratoryDana-FarberCancerInstituteimplementnovelphysicianmultidisciplinaryformedaccomplishtaskdevelopingidentifiedcharacteristicssoughtneedsdevelopedimplementedincludesthreeinterrelatedaddressesrequirementstraditionalproviderwellpatientconcernsstreamlinedreducedopportunitieserrordelayDevelopmentimplementationcollection

Similar Articles

Cited By

No available data.