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BioMed research international
2013;2013 462179.

Stem cell therapy for lower extremity diabetic ulcers: where do we stand?

Mei Yang, Lingling Sheng, Tian R Zhang, Qingfeng Li
Author Information
  1. Mei Yang: Division of Plastic Surgery, Southern Illinois University School of Medicine, Springfield, IL 62794, USA.
PMID: 23586040 DOI: 10.1155/2013/462179

Abstract

The impairment of wound healing in diabetic patients is an important clinical problem affecting millions of patients worldwide. Various clinical and basic science studies show that stem cell therapy, as a regenerative medical therapy, can be a good solution. In this paper, we begin with an introduction of the cellular mechanism of the diabetic ulcer. We will then discuss the advantages and limitations of various stem cell therapies that have been under extensive recent study.

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MeSH Term

Cell- and Tissue-Based Therapy
Diabetes Complications
Diabetic Foot
Humans
Lower Extremity
Neovascularization, Physiologic
Stem Cell Transplantation
Wound Healing
Journal Article Review
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