Knowledge of pre-exposure prophylaxis (PrEP) for HIV prevention among men who have sex with men in Denver, Colorado.

Alia A Al-Tayyib, Mark W Thrun, Jason S Haukoos, N Eugene Walls
Author Information
  1. Alia A Al-Tayyib: Denver Public Health, Denver Health and Hospital Authority, 605 Bannock Street, Denver, CO, 80204-4507, USA, alia.al-tayyib@dhha.org.

Abstract

As part of the National HIV Behavioral Surveillance System among men who have sex with men (MSM) in Denver, Colorado, we assessed knowledge of pre-exposure prophylaxis (PrEP); willingness to use PrEP; and potential changes in risk behaviors among HIV-negative participants reporting sexual activity with a male partner in the preceding 12 months. We examined knowledge of PrEP before (2008) and after (2011) results of the iPrEx trial were available. Of the 425 participants in the 2008 sample, 91 (21 %) were aware of PrEP compared to 131 (28 %) of the 461 participants in the 2011 sample (adjusted prevalence ratio: 1.43, 95 % confidence interval: 1.18, 1.72). Despite the increase in 2011, few MSM in Denver were aware of PrEP. Educating high-risk MSM about the potential utility of PrEP as an adjunct to other effective prevention methods is needed when considering the addition of PrEP to the HIV prevention arsenal.

References

  1. J Acquir Immune Defic Syndr. 2008 Feb 1;47(2):241-7 [PMID: 18340656]
  2. MMWR Morb Mortal Wkly Rep. 2012 Aug 10;61(31):586-9 [PMID: 22874836]
  3. Curr Infect Dis Rep. 2012 Apr;14(2):185-93 [PMID: 22351302]
  4. AIDS Clin Care. 2009 Jan;21(1):6 [PMID: 19226670]
  5. J Acquir Immune Defic Syndr. 2009 Jan 1;50(1):77-83 [PMID: 19295337]
  6. Ann Intern Med. 2007 Apr 17;146(8):591-601 [PMID: 17438318]
  7. MMWR Morb Mortal Wkly Rep. 2011 Jan 28;60(3):65-8 [PMID: 21270743]
  8. Health Aff (Millwood). 2012 Jul;31(7):1439-49 [PMID: 22778333]
  9. N Engl J Med. 2011 Aug 11;365(6):493-505 [PMID: 21767103]
  10. AIDS Behav. 2013 Jul;17(6):2180-4 [PMID: 23479003]
  11. J Int Assoc Physicians AIDS Care (Chic). 2003 Jul-Sep;2(3):102-5 [PMID: 14556428]
  12. PLoS One. 2012;7(1):e28238 [PMID: 22247757]
  13. Curr Opin Infect Dis. 2007 Feb;20(1):1-2 [PMID: 17197874]
  14. N Engl J Med. 2012 Aug 2;367(5):423-34 [PMID: 22784038]
  15. MMWR Morb Mortal Wkly Rep. 2013 Jun 14;62(23):463-5 [PMID: 23760186]
  16. AIDS Behav. 2011 Apr;15 Suppl 1:S72-9 [PMID: 21331801]
  17. N Engl J Med. 2010 Dec 30;363(27):2587-99 [PMID: 21091279]
  18. AIDS Behav. 2014 Feb;18(2):241-9 [PMID: 23673790]
  19. Public Health Rep. 2007;122 Suppl 1:32-8 [PMID: 17354525]
  20. Implement Sci. 2012 Nov 26;7:116 [PMID: 23181780]
  21. Curr HIV Res. 2012 Mar;10(2):117-22 [PMID: 22329517]
  22. PLoS One. 2012;7(3):e33119 [PMID: 22470438]
  23. Lancet. 2012 Jun 30;379(9835):2409-2411 [PMID: 22153566]
  24. J Acquir Immune Defic Syndr. 2006 Nov 1;43(3):376-7 [PMID: 17079995]
  25. J Acquir Immune Defic Syndr. 2010 Oct;55(2):e14-6 [PMID: 20859085]
  26. N Engl J Med. 2012 Aug 2;367(5):399-410 [PMID: 22784037]
  27. J Acquir Immune Defic Syndr. 2010 Aug;54(5):548-55 [PMID: 20512046]
  28. J Acquir Immune Defic Syndr. 2007 Nov 1;46(3):378-80 [PMID: 18090305]
  29. PLoS One. 2012;7(11):e50061 [PMID: 23166819]

Grants

  1. R01 AI106057/NIAID NIH HHS
  2. U62 PS000954/NCHHSTP CDC HHS
  3. U62-PS000954/NCHHSTP CDC HHS

MeSH Term

Adult
Behavioral Risk Factor Surveillance System
Colorado
Condoms
HIV Infections
Health Knowledge, Attitudes, Practice
Homosexuality, Male
Humans
Interviews as Topic
Male
Middle Aged
Multivariate Analysis
Primary Prevention
Sexual Partners
Socioeconomic Factors
Surveys and Questionnaires
Unsafe Sex
Young Adult

Word Cloud

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