Genetic counseling for breast cancer risk: how did we get here and where are we going?

Katherine Af Lang
Author Information
  1. Katherine Af Lang: Northside Hospital Cancer Institute, 1000 Johnson Ferry Rd NE, Atlanta, GA 30342, USA. katie.lang@northside.com

Abstract

Genetic counselors have been helping patients navigate hereditary cancer risk for decades. The rapidly changing landscape of genetic testing options means the field is again at a unique time in its history. Fears that arose when BRCA testing first became available are again being voiced in light of next-generation sequencing. The origins of genetic counseling, best practices, and recommendations that have come about since those early days need to be well understood before these new challenges can be met. The role of a proper risk assessment in preventing adverse outcomes is vital as options for testing change. In addition, an understanding of how various countries have incorporated genetic testing and genetic counseling into their healthcare systems can provide lessons in moving forward and capitalizing on the new technology that is again creating a genetics revolution.

MeSH Term

BRCA1 Protein
BRCA2 Protein
Breast Neoplasms
Female
Genetic Counseling
Genetic Predisposition to Disease
High-Throughput Nucleotide Sequencing
Humans
Risk Assessment

Chemicals

BRCA1 Protein
BRCA1 protein, human
BRCA2 Protein
BRCA2 protein, human

Word Cloud

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