Use transition between illegal drugs among Brazilian university students.

João Mauricio Castaldelli-Maia, Silvia S Martins, Lúcio Garcia de Oliveira, Margriet van Laar, Arthur Guerra de Andrade, Sergio Nicastri
Author Information
  1. João Mauricio Castaldelli-Maia: Interdisciplinary Group of Studies on Alcohol and Drugs (GREA), Institute of Psychiatry, Medical School, University of São Paulo, Rua Dr. Ovídio Pires de Campos, 785 (GREA), São Paulo, SP, 05403-903, Brazil, jmcmaia2@gmail.com.

Abstract

PURPOSE: The aim of the present study was to test whether the first use of an illicit drug increases the chance of first use of other illicit drugs.
METHOD: The transitions from the first use of a drug to the first use of another drug were analyzed. Comparisons were made between first drug users and non-users. Survival analysis methods were used to compare the cumulative probability of second drug use after adjusting for socio-demographic covariates and the intermediate use of alcohol and/or tobacco. A total of 12,721 Brazilian university students participated in this study.
RESULTS: Inhalants and marijuana were used prior to the use of several other drugs, whereas the opposite pattern was not found. Ecstasy was used before other drugs in several instances. Other well-examined drugs, such as amphetamines, cocaine and hallucinogens, were used both before and after other illicit drugs without any marked predominance for either of the two roles.
CONCLUSIONS: This study supports the role of the use of marijuana and inhalants almost exclusively before the use of other illicit drugs, whereas the use of ecstasy has an opposite role. These roles could be linked to the prevalence of lifetime use and whether individuals were at an earlier or later age during experimentation.

References

  1. Drug Alcohol Depend. 2009 Jun 1;102(1-3):30-4 [PMID: 19328635]
  2. J Stud Alcohol Drugs. 2008 Nov;69(6):789-95 [PMID: 18925336]
  3. Arch Gen Psychiatry. 1975 Jul;32(7):923-32 [PMID: 1156108]
  4. Int J Drug Policy. 2009 May;20(3):237-43 [PMID: 18554892]
  5. Drug Alcohol Depend. 1997 Dec;49(1):1-7 [PMID: 9476693]
  6. Drug Alcohol Depend. 2013 Sep 1;132(1-2):107-13 [PMID: 23399466]
  7. Am J Drug Alcohol Abuse. 2009;35(6):445-53 [PMID: 20014915]
  8. Drug Alcohol Depend. 2009 Jan 1;99(1-3):58-67 [PMID: 18706774]
  9. Subst Use Misuse. 2011;46 Suppl 1:27-34 [PMID: 21609142]
  10. Am J Epidemiol. 2002 May 15;155(10):918-25 [PMID: 11994231]
  11. Addiction. 2002 Dec;97(12):1493-504 [PMID: 12472629]
  12. J Drug Educ. 2009;39(3):261-72 [PMID: 20196331]
  13. Science. 1975 Nov 28;190(4217):912-4 [PMID: 1188374]
  14. Addict Behav. 2010 Oct;35(10):890-5 [PMID: 20584572]
  15. Am J Drug Alcohol Abuse. 2008;34(6):782-91 [PMID: 19016184]
  16. Neuropsychobiology. 2013;67(4):241-8 [PMID: 23689792]
  17. Int J Epidemiol. 1987 Jun;16(2):167-70 [PMID: 3610443]
  18. Braz J Psychiatry. 2012 Oct;34(3):294-305 [PMID: 23429775]
  19. Int J Eat Disord. 2006 Jul;39(5):364-8 [PMID: 16565976]
  20. Lancet. 2012 Jan 7;379(9810):55-70 [PMID: 22225671]
  21. Drug Alcohol Rev. 2005 Mar;24(2):185-91 [PMID: 16076588]
  22. Addiction. 2002 Dec;97(12):1509-10 [PMID: 12472633]
  23. Braz J Psychiatry. 2005 Sep;27(3):185-93 [PMID: 16224605]
  24. Ann Epidemiol. 2007 Jan;17(1):74-80 [PMID: 17140814]
  25. Drug Alcohol Depend. 2010 Apr 1;108(1-2):84-97 [PMID: 20060657]
  26. Addiction. 2008 Aug;103(8):1361-70 [PMID: 18855826]
  27. Drug Alcohol Depend. 2009 Jan 1;99(1-3):68-78 [PMID: 18768267]
  28. J Subst Abuse Treat. 2010 Mar;38(2):178-90 [PMID: 19717274]
  29. NIDA Res Monogr. 1994;142:196-263 [PMID: 9243538]
  30. Braz J Psychiatry. 2007 Jun;29(2):123-9 [PMID: 17650531]
  31. Ann Agric Environ Med. 2012;19(3):491-6 [PMID: 23020045]
  32. Drug Alcohol Depend. 2008 Jul 1;96(1-2):165-77 [PMID: 18423900]
  33. Rev Bras Epidemiol. 2011 Sep;14 Suppl 1:136-46 [PMID: 22002150]
  34. Drug Alcohol Depend. 2010 Nov 1;112(1-2):69-80 [PMID: 20580168]
  35. Drug Alcohol Depend. 2009 Jun 1;102(1-3):78-87 [PMID: 19250776]
  36. Med Anthropol Q. 1998 Dec;12(4):424-46 [PMID: 9884992]
  37. BMC Public Health. 2009 Jan 21;9:27 [PMID: 19159468]
  38. Drug Alcohol Depend. 2007 May 11;88(2-3):272-81 [PMID: 17174040]
  39. Bioessays. 2010 Sep;32(9):748-55 [PMID: 20730946]
  40. Subst Use Misuse. 2013 Feb;48(3):248-57 [PMID: 23302060]
  41. Am J Public Health. 2011 May;101(5):948-54 [PMID: 21421952]
  42. Cochrane Database Syst Rev. 2010 Nov 10;(11):CD001006 [PMID: 21069667]
  43. Drug Alcohol Depend. 2002 Apr 1;66(2):127-35 [PMID: 11906800]
  44. Lancet. 2012 Jan 7;379(9810):71-83 [PMID: 22225672]
  45. Cien Saude Colet. 2010 May;15(3):663-70 [PMID: 20464178]
  46. Salud Publica Mex. 2004 Mar-Apr;46(2):132-40 [PMID: 15176575]
  47. Addiction. 2006 Apr;101(4):556-69 [PMID: 16548935]

Grants

  1. R21 DA020667/NIDA NIH HHS
  2. DA020667/NIDA NIH HHS
  3. R03 DA023434/NIDA NIH HHS
  4. HD060072/NICHD NIH HHS
  5. DA023434/NIDA NIH HHS

MeSH Term

Adolescent
Brazil
Drug Users
Female
Humans
Illicit Drugs
Male
Prevalence
Students
Universities
Young Adult

Chemicals

Illicit Drugs

Word Cloud

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