- Sreeman K Mamidyala: Institute for Molecular Bioscience, University of Queensland, St Lucia, QLD 4072, Australia. s.mamidyala@uq.edu.au m.cooper@uq.edu.au.
A new method for the synthesis of N-substituted isoindolinones and 3-arylaminophthalides was developed through aza-Wittig/cyclisation. The reaction of o-phthalaldehydic acid methyl ester with benzylic, aromatic and aliphatic azides gave N-isoindolinones whereas reaction of o-phthalaldehydic acid with the aromatic azides gave 3-arylaminophthalides.