Relationship of selected bacterial vaginosis-associated bacteria to Nugent score bacterial vaginosis among urban women early in pregnancy.

Deborah B Nelson, Eugene Komaroff, Irving Nachamkin, Catherine L Haggerty, LaVette Dibble, Dimitrios Mastrogiannis, Congzhou Liu, David N Fredricks, Fredricks N David
Author Information
  1. Deborah B Nelson: Department of Obstetrics and Gynecology, Temple University, Philadelphia, PA 19122, USA. dnelson@temple.edu

Abstract

Among urban, primarily African American pregnant women, 74% were identified with Nugent score bacterial vaginosis (BV). All BV-associated bacteria were more prevalent among women with Nugent score BV. Bacterial vaginosis-associated bacteria 3 (BVAB3) had the highest positive predictive value, whereas Gardnerella vaginalis and Atopobium spp. had the highest sensitivity. Atopobium spp. levels had the most significant area under the curve.

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Grants

  1. R01 HD038856/NICHD NIH HHS
  2. R01HD038856/NICHD NIH HHS

MeSH Term

Actinobacteria
Black or African American
Area Under Curve
Colony Count, Microbial
Female
Gardnerella vaginalis
Humans
Pregnancy
Pregnancy Complications, Infectious
Prevalence
Sensitivity and Specificity
Urban Population
Vagina
Vaginosis, Bacterial