Right-sided infective endocarditis: recent epidemiologic changes.

Shi-Min Yuan
Author Information
  1. Shi-Min Yuan: Department of Cardiothoracic Surgery, The First Hospital of Putian, Teaching Hospital, Fujian Medical University Putian, Fujian Province, China.

Abstract

BACKGROUND: Infective endocarditis (IE) has been increasingly reported, however, little is available regarding recent development of right-sided IE.
METHODS: Right-sided IE was comprehensively analyzed based on recent 5⅓-year literature.
RESULTS: Portal of entry, implanted foreign material, and repaired congenital heart defects were the main predisposing risk factors. Vegetation size on the right-sided valves was much smaller than those beyond the valves. Multiple logistic regression analysis revealed that predisposing risk factors, and vegetation size and locations were independent predictive risks of patients' survival.
CONCLUSIONS: Changes of right-sided IE in the past 5⅓ years included younger patient age, and increased vegetation size, but still prominent Staphylococcus aureus infections. Complication spectrum has changed into more valve insufficiency, more embolic events, reduced abscess formation, and considerably decreased valve perforations. With effective antibiotic regimens, prognoses of the patients seemed to be better than before.

Keywords

References

  1. Tex Heart Inst J. 2010;37(1):99-101 [PMID: 20200638]
  2. Echocardiography. 2008 May;25(5):511-3 [PMID: 18279398]
  3. Heart. 2005 Jul;91(7):932-7 [PMID: 15958364]
  4. J Antimicrob Chemother. 2011 Mar;66(3):679-82 [PMID: 21393234]
  5. Hellenic J Cardiol. 2010 Nov-Dec;51(6):538-9 [PMID: 21169186]
  6. Heart Lung Circ. 2010 Sep;19(9):566-71 [PMID: 20541971]
  7. Case Rep Infect Dis. 2011;2011:981316 [PMID: 22567485]
  8. Ann Pediatr Cardiol. 2011 Jan;4(1):77-80 [PMID: 21677814]
  9. J Assoc Physicians India. 2011 Mar;59:184-6 [PMID: 21751635]
  10. Can Respir J. 2011 May-Jun;18(3):e48-9 [PMID: 21766083]
  11. Chest. 2003 Oct;124(4):1451-9 [PMID: 14555579]
  12. Case Rep Infect Dis. 2012;2012:841834 [PMID: 22957282]
  13. J Infect. 2011 Dec;63(6):420-8 [PMID: 21920382]
  14. Heart Lung. 2012 Jul-Aug;41(4):387-9 [PMID: 21983217]
  15. Intern Med. 2008;47(15):1437-40 [PMID: 18670152]
  16. J Cardiothorac Vasc Anesth. 2010 Feb;24(1):211-3 [PMID: 19285428]
  17. J Med Case Rep. 2010 Aug 04;4:245 [PMID: 20684779]
  18. Am Heart J. 1989 May;117(5):1140-6 [PMID: 2653011]
  19. J Thorac Cardiovasc Surg. 2007 Jan;133(1):144-9 [PMID: 17198801]
  20. ISRN Cardiol. 2011;2011:492543 [PMID: 22347645]
  21. Medicine (Baltimore). 2009 Jan;88(1):1-22 [PMID: 19352296]
  22. Ann Pediatr Cardiol. 2010 Jul;3(2):174-7 [PMID: 21234200]
  23. Can J Cardiol. 2008 Aug;24(8):e54-5 [PMID: 18685750]
  24. Am J Med Sci. 2003 May;325(5):282-4 [PMID: 12792247]
  25. Gen Thorac Cardiovasc Surg. 2009 Aug;57(8):418-20 [PMID: 19779790]
  26. J Am Soc Echocardiogr. 2009 Feb;22(2):210.e1-3 [PMID: 19135858]
  27. Oman Med J. 2011 Sep;26(5):365-7 [PMID: 22125735]
  28. Thorac Cardiovasc Surg. 2011 Mar;59(2):123-5 [PMID: 21384311]
  29. Case Rep Med. 2010;2010: [PMID: 20885942]
  30. Ann Thorac Surg. 2010 Mar;89(3):959-61 [PMID: 20172166]
  31. J Heart Valve Dis. 2011 Mar;20(2):223-8 [PMID: 21560826]
  32. Postgrad Med J. 2012 Jul;88(1041):377-81 [PMID: 22366395]
  33. Obstet Gynecol. 2008 Aug;112(2 Pt 2):452-5 [PMID: 18669761]
  34. Int J Antimicrob Agents. 2008 Dec;32(6):544-5 [PMID: 18789850]
  35. Hawaii Med J. 2010 Dec;69(12):286-8 [PMID: 21225584]
  36. Int J Infect Dis. 2009 Sep;13(5):e267-9 [PMID: 19121968]
  37. Pacing Clin Electrophysiol. 2011 Dec;34(12):e115-7 [PMID: 20636317]
  38. Intern Med. 2013;52(7):835 [PMID: 23545689]
  39. Clin Res Cardiol. 2010 Jul;99(7):471-3 [PMID: 20306267]
  40. Eur Heart J Cardiovasc Imaging. 2012 Apr;13(4):330-8 [PMID: 22109247]
  41. Ann Thorac Surg. 2008 Nov;86(5):1670-2 [PMID: 19049772]
  42. Eur Heart J. 2007 Jan;28(2):196-203 [PMID: 17158121]
  43. Korean J Thorac Cardiovasc Surg. 2011 Jun;44(3):240-2 [PMID: 22263159]
  44. Clin Cardiol. 2012 Apr;35(4):244-9 [PMID: 22213472]
  45. J Am Soc Echocardiogr. 2008 Jun;21(6):776.e1-3 [PMID: 17961978]
  46. J Thorac Cardiovasc Surg. 2010 May;139(5):e99-e100 [PMID: 19660360]
  47. J Cardiovasc Dis Res. 2012 Jul;3(3):236-9 [PMID: 22923944]
  48. Heart Lung Circ. 2011 Jun;20(6):362-4 [PMID: 21514218]
  49. Monaldi Arch Chest Dis. 2008 Jun;69(2):75-7 [PMID: 18837421]
  50. Acta Cardiol. 2010 Dec;65(6):707-8 [PMID: 21302681]
  51. Rev Port Cardiol. 2012 Sep;31(9):615-7 [PMID: 22857915]
  52. Cardiovasc Pathol. 2010 Jul-Aug;19(4):e137-9 [PMID: 19211274]
  53. Eur J Cardiothorac Surg. 2007 Jul;32(1):118-25 [PMID: 17412606]
  54. J Heart Valve Dis. 2009 Mar;18(2):167-9 [PMID: 19455891]
  55. Rev Soc Bras Med Trop. 2012 Mar-Apr;45(2):272-4 [PMID: 22535008]
  56. J Thorac Cardiovasc Surg. 2009 Jun;137(6):1564-5 [PMID: 19464487]
  57. J Cardiothorac Surg. 2009 Feb 24;4:12 [PMID: 19239701]
  58. JACC Cardiovasc Imaging. 2010 Mar;3(3):325-7 [PMID: 20223431]
  59. J Cardiothorac Vasc Anesth. 2008 Apr;22(2):261-2 [PMID: 18375331]
  60. Heart Lung. 2012 May;41(3):301-7 [PMID: 21893344]
  61. Interact Cardiovasc Thorac Surg. 2013 Mar;16(3):384-6 [PMID: 23243038]
  62. Heart Lung Circ. 2012 Mar;21(3):189-92 [PMID: 21920817]
  63. BMC Nephrol. 2012 Dec 26;13:174 [PMID: 23268737]
  64. Scand J Infect Dis. 2012 Jul;44(7):544-7 [PMID: 22385220]
  65. J Cardiol. 2009 Feb;53(1):146-9 [PMID: 19167651]
  66. Can J Cardiol. 2010 Aug-Sep;26(7):e280-1 [PMID: 20847979]
  67. J Perinatol. 2009 Sep;29(9):643-5 [PMID: 19710658]
  68. Int J Cardiol. 2011 Nov 17;153(1):e15-8 [PMID: 21353714]
  69. N Z Med J. 2011 Aug 12;124(1340):84-6 [PMID: 21952388]
  70. J Am Soc Echocardiogr. 2011 May;24(5):592.e1-3 [PMID: 20833508]
  71. Am J Med. 2007 Oct;120(10 Suppl 1):S28-33 [PMID: 17904948]
  72. J Assoc Physicians India. 2010 May;58:319-22 [PMID: 21117353]
  73. BMJ. 2012 Mar 13;344:e1568 [PMID: 22415952]
  74. W V Med J. 2009 Jan-Feb;105(1):18-9 [PMID: 19146042]
  75. Ann Thorac Surg. 2008 Jun;85(6):2128-30 [PMID: 18498842]
  76. Echocardiography. 2013 Jul;30(6):E167-70 [PMID: 23551809]
  77. Can J Cardiol. 2000 Oct;16(10):1282-8 [PMID: 11064303]
  78. J Cardiovasc Ultrasound. 2009 Dec;17(4):138-40 [PMID: 20661339]
  79. Pediatr Cardiol. 2012 Dec;33(8):1461-2 [PMID: 22695764]
  80. Can J Cardiol. 2011 Mar-Apr;27(2):263.e17-20 [PMID: 21459281]
  81. Crit Ultrasound J. 2013 Feb 11;5(1):1 [PMID: 23399454]
  82. J Cardiol. 2014 Feb;63(2):145-8 [PMID: 23906529]
  83. Eur J Echocardiogr. 2007 Dec;8(6):501-3 [PMID: 17045549]
  84. Int J Cardiol. 2008 Jul 21;127(3):e129-31 [PMID: 17692958]
  85. Ann Thorac Cardiovasc Surg. 2010 Apr;16(2):134-8 [PMID: 20930670]
  86. Eur J Intern Med. 2009 Mar;20(2):e32-3 [PMID: 19327593]
  87. Arch Cardiovasc Dis. 2008 Nov-Dec;101(11-12):793-4 [PMID: 19059575]
  88. Diagn Microbiol Infect Dis. 2009 Jun;64(2):216-9 [PMID: 19376668]
  89. Eur J Cardiothorac Surg. 2008 Nov;34(5):1115-7 [PMID: 18755597]
  90. Ann Intern Med. 1988 Oct 15;109(8):619-24 [PMID: 3421575]
  91. Eur Heart J. 2009 Jan;30(1):97 [PMID: 18603623]
  92. Cardiovasc Pathol. 2009 Jul-Aug;18(4):231-5 [PMID: 18703355]
  93. Rev Port Cardiol. 2013 Jan;32(1):53-8 [PMID: 23237844]
  94. J Am Coll Cardiol. 1993 Apr;21(5):1226-30 [PMID: 8459081]
  95. Cardiol Young. 2011 Aug;21(4):458-9 [PMID: 21262070]
  96. J Card Surg. 2009 Nov-Dec;24(6):667-9 [PMID: 20078712]
  97. Echocardiography. 2008 Sep;25(8):904-7 [PMID: 18986419]
  98. Ann Thorac Surg. 2011 May;91(5):1414-9 [PMID: 21524451]
  99. Can J Cardiol. 2009 Jul;25(7):429-31 [PMID: 19584975]
  100. Am J Med Sci. 2012 Apr;343(4):328-9 [PMID: 22270403]
  101. J Card Surg. 2011 Nov;26(6):650-2 [PMID: 21950324]
  102. BMJ Case Rep. 2013 Mar 11;2013: [PMID: 23483061]
  103. J Infect. 2008 Aug;57(2):132-8 [PMID: 18597851]
  104. Scand J Infect Dis. 2009;41(1):73-5 [PMID: 18985544]
  105. Europace. 2011 Nov;13(11):1653-7 [PMID: 21712260]
  106. Heart Surg Forum. 2011 Dec;14(6):E357-9 [PMID: 22167761]
  107. Arch Intern Med. 2009 Mar 9;169(5):463-73 [PMID: 19273776]
  108. Burns. 2008 Aug;34(5):610-6 [PMID: 18029099]
  109. J Obstet Gynaecol. 2011;31(1):78-80 [PMID: 21281001]
  110. J Gen Intern Med. 2011 Oct;26(10):1209-11 [PMID: 21538169]
  111. Interact Cardiovasc Thorac Surg. 2009 Feb;8(2):280-2 [PMID: 19042930]
  112. Can J Cardiol. 2012 Mar-Apr;28(2):245.e13-5 [PMID: 22305417]
  113. J Thorac Cardiovasc Surg. 2008 Aug;136(2):531-2 [PMID: 18692673]
  114. Thorac Cardiovasc Surg. 2012 Jul;60(5):363-5 [PMID: 21557164]
  115. Am Heart J. 2005 Nov;150(5):1099-106 [PMID: 16291005]
  116. Heart Lung. 2008 Nov-Dec;37(6):479-80 [PMID: 18992632]
  117. Am Surg. 2009 Dec;75(12):1265-6 [PMID: 19999930]
  118. Asian Cardiovasc Thorac Ann. 2012 Feb;20(1):58-60 [PMID: 22371944]
  119. Pediatr Cardiol. 2010 May;31(4):553-5 [PMID: 20063157]
  120. J Microbiol Immunol Infect. 2010 Oct;43(5):430-7 [PMID: 21075710]
  121. Indian Heart J. 2011 May-Jun;63(3):237-40 [PMID: 22734342]
  122. Ann Thorac Surg. 2010 Apr;89(4):1180-5 [PMID: 20338328]
  123. Br J Dermatol. 2011 Jun;164(6):1405-6 [PMID: 21615373]
  124. Heart Lung. 2011 Mar-Apr;40(2):172-6 [PMID: 20800283]
  125. Arch Immunol Ther Exp (Warsz). 2012 Jun;60(3):221-3 [PMID: 22487784]
  126. BMJ Case Rep. 2013 Feb 14;2013: [PMID: 23417387]
  127. Clin Microbiol Infect. 2009 Apr;15(4):387-94 [PMID: 19260876]
  128. Congenit Heart Dis. 2013 Nov-Dec;8(6):E161-4 [PMID: 23095520]
  129. Gen Thorac Cardiovasc Surg. 2011 Jun;59(6):429-32 [PMID: 21674312]
  130. J Postgrad Med. 2010 Apr-Jun;56(2):143-5 [PMID: 20622395]
  131. Intensive Care Med. 2012 Dec;38(12):2081-2 [PMID: 22878350]
  132. Ann Thorac Cardiovasc Surg. 2010 Jun;16(3):207-9 [PMID: 20930685]
  133. Postgrad Med J. 1993 Aug;69(814):615-20 [PMID: 8234104]
  134. BMJ Case Rep. 2013 Jan 25;2013: [PMID: 23355575]
  135. Ann Thorac Surg. 2010 Apr;89(4):1299-300 [PMID: 20338367]
  136. Isr Med Assoc J. 2007 May;9(5):365-9 [PMID: 17591374]
  137. J Med Case Rep. 2012 Aug 14;6:242 [PMID: 22892203]
  138. Eur Heart J. 2011 May;32(10):1299 [PMID: 21193436]
  139. J Cardiovasc Med (Hagerstown). 2015 Jan;16 Suppl 2:S122-4 [PMID: 20671573]
  140. Interact Cardiovasc Thorac Surg. 2008 May;7(3):513-4 [PMID: 18296475]
  141. J Card Surg. 2012 Jul;27(4):449-52 [PMID: 22381119]
  142. Clin Cardiol. 2009 Dec;32(12):E48-54 [PMID: 20014189]
  143. Ann Thorac Surg. 2010 Apr;89(4):1187-94 [PMID: 20338330]
  144. Clin Infect Dis. 2009 May 15;48 Suppl 4:S231-7 [PMID: 19374578]
  145. Gen Thorac Cardiovasc Surg. 2011 Jul;59(7):483-4 [PMID: 21751108]
  146. J Cardiothorac Surg. 2008 Jul 16;3:46 [PMID: 18627635]
  147. J Vasc Interv Radiol. 2008 May;19(5):783-4 [PMID: 18440471]
  148. Infection. 2007 Jun;35(3):154-60 [PMID: 17565456]
  149. Int J Infect Dis. 2010 Sep;14 Suppl 3:e196-7 [PMID: 19900829]
  150. Korean J Thorac Cardiovasc Surg. 2013 Feb;46(1):60-2 [PMID: 23423378]
  151. J Microbiol Immunol Infect. 2012 Jun;45(3):248-50 [PMID: 22041168]
  152. Ann Pharmacother. 2010 Apr;44(4):746-9 [PMID: 20197474]
  153. Medicine (Baltimore). 2009 Sep;88(5):294-301 [PMID: 19745688]
  154. Int J Cardiol. 2012 Nov 29;161(3):e44-5 [PMID: 22521380]
  155. Int J Antimicrob Agents. 2012 Aug;40(2):145-50 [PMID: 22727531]
  156. BMJ Open. 2013 Mar 25;3(3): [PMID: 23533214]
  157. Int J Cardiol. 2008 Jun 6;126(3):e47-9 [PMID: 17395320]
  158. Echocardiography. 2008 Jul;25(6):642-5 [PMID: 18479359]
  159. J Am Soc Echocardiogr. 2010 Jul;23(7):791.e5-7 [PMID: 20097530]
  160. Eur J Pediatr. 2011 Sep;170(9):1111-27 [PMID: 21773669]
  161. Int J Infect Dis. 2009 May;13(3):e109-11 [PMID: 18986821]
  162. Obstet Med. 2010 Jun;3(2):78-80 [PMID: 27582848]
  163. J Heart Valve Dis. 2011 Jan;20(1):94-7 [PMID: 21404904]
  164. J Cardiothorac Vasc Anesth. 2008 Jun;22(3):495-6 [PMID: 18503948]
  165. Am J Med Sci. 1997 Sep;314(3):207-12 [PMID: 9298048]
  166. Indian J Med Microbiol. 2010 Jan-Mar;28(1):72-3 [PMID: 20061772]
  167. J Heart Valve Dis. 2000 May;9(3):353-7; discussion 357-8 [PMID: 10888090]
  168. J Card Surg. 2010 Mar;25(2):153-5 [PMID: 20136672]
  169. Ann Thorac Surg. 2009 Dec;88(6):2027-9 [PMID: 19932290]
  170. Congenit Heart Dis. 2011 Nov-Dec;6(6):638-40 [PMID: 21545467]
  171. J Am Coll Cardiol. 2012 Jun 5;59(23):e45 [PMID: 22651875]
  172. Heart Views. 2010 Oct;11(3):121-4 [PMID: 21577381]
  173. J Card Surg. 2012 Jan;27(1):93-8 [PMID: 22074086]
  174. Medicine (Baltimore). 2011 Jul;90(4):231-236 [PMID: 21694644]
  175. Perfusion. 2010 May;25(3):169-73 [PMID: 20581029]
  176. J Microbiol Immunol Infect. 2009 Feb;42(1):92-5 [PMID: 19424564]
  177. Hosp Pract (1995). 2013 Feb;41(1):117-21 [PMID: 23466974]
  178. BMC Pediatr. 2013 Apr 22;13:61 [PMID: 23607627]
  179. Nihon Ishinkin Gakkai Zasshi. 2010;51(4):207-10 [PMID: 21060214]
  180. Ann Thorac Surg. 2009 Jun;87(6):1954-6 [PMID: 19463639]
  181. BMC Infect Dis. 2012 Sep 27;12:231 [PMID: 23013220]
  182. Arch Cardiol Mex. 2012 Jul-Sep;82(3):204-7 [PMID: 23021356]
  183. Ann Thorac Cardiovasc Surg. 2012;18(5):481-4 [PMID: 22446954]
  184. Can J Infect Dis Med Microbiol. 2011 Fall;22(3):e17-20 [PMID: 22942890]
  185. Cardiovasc Ultrasound. 2010 Sep 30;8:44 [PMID: 20920293]
  186. Cardiol Res Pract. 2010 Dec 26;2010:798956 [PMID: 21234101]
  187. Transpl Infect Dis. 2009 Aug;11(4):346-8 [PMID: 19497075]
  188. J Thorac Cardiovasc Surg. 2010 Apr;139(4):e71-2 [PMID: 20304127]
  189. Korean Circ J. 2011 Aug;41(8):482-5 [PMID: 21949535]
  190. Singapore Med J. 2009 Apr;50(4):e124-6 [PMID: 19421664]
  191. Thorac Cardiovasc Surg. 2009 Jun;57(4):196-201 [PMID: 19670110]
  192. J Thorac Cardiovasc Surg. 2013 Oct;146(4):841-7 [PMID: 22939859]
  193. Rev Esp Cardiol. 1998;51 Suppl 2:71-8 [PMID: 9658952]
  194. Ann Thorac Surg. 2010 Feb;89(2):643-5 [PMID: 20103373]
  195. Pacing Clin Electrophysiol. 2009 Sep;32(9):1237-9 [PMID: 19719505]
  196. Pediatr Infect Dis J. 2010 Sep;29(9):886-8 [PMID: 20495509]
  197. J Heart Valve Dis. 2010 Sep;19(5):674-5 [PMID: 21053751]
  198. Asian Cardiovasc Thorac Ann. 2011 Dec;19(6):414-5 [PMID: 22160412]
  199. Can J Cardiol. 2009 Apr;25(4):e130-2 [PMID: 19340358]

Word Cloud

Created with Highcharts 10.0.0IErecentright-sidedsizeRight-sidedpredisposingriskfactorsvalvesvegetationvalveBACKGROUND:InfectiveendocarditisincreasinglyreportedhoweverlittleavailableregardingdevelopmentMETHODS:comprehensivelyanalyzedbased5⅓-yearliteratureRESULTS:PortalentryimplantedforeignmaterialrepairedcongenitalheartdefectsmainVegetationmuchsmallerbeyondMultiplelogisticregressionanalysisrevealedlocationsindependentpredictiveriskspatients'survivalCONCLUSIONS:Changespast5⅓yearsincludedyoungerpatientageincreasedstillprominentStaphylococcusaureusinfectionsComplicationspectrumchangedinsufficiencyemboliceventsreducedabscessformationconsiderablydecreasedperforationseffectiveantibioticregimensprognosespatientsseemedbetterbeforeinfectiveendocarditis:epidemiologicchangesAnti-bacterialagentsblood-bornepathogenscardiacsurgicalprocedurescomplicationsembolism

Similar Articles

Cited By