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Environmental science and pollution research international
Dec, 2014;21 (24): 13877-87.

Long-term disruption of growth, reproduction, and behavior after embryonic exposure of zebrafish to PAH-spiked sediment.

Caroline Vignet, Marie-Hélène Devier, Karyn Le Menach, Laura Lyphout, Jérémy Potier, Jérôme Cachot, Hélène Budzinski, Marie-Laure Bégout, Xavier Cousin
Author Information
  1. Caroline Vignet: Laboratoire d'Ecotoxicologie, Ifremer, Place Gaby Coll, BP7, 17137, L'Houmeau, France.
PMID: 24659400 DOI: 10.1007/s11356-014-2585-5

Abstract

A natural sediment spiked with three individual polycyclic aromatic hydrocarbons (PAHs; pyrene, phenanthrene and benzo[a]pyrene) was used to expose zebrafish embryos and larvae during 4 days. The total PAH concentration was 4.4 μg g(-1) which is in the range found in sediment from contaminated areas. Quantification of metabolites in the larvae after exposure confirmed the actual contamination of the larvae and indicated an active metabolism especially for pyrene and benzo[a]pyrene. After a transfer in a clean medium, the larvae were reared to adulthood and evaluated for survival, growth, reproduction, and behavior. Measured endpoints revealed a late disruption of growth (appearing at 5 months) and a trend toward a lower reproductive ability. Adults of embryos exposed to sediment spiked with PAHs displayed lethargic and/or anxiety-like behaviors. This latter behavior was also identified in offspring at larval stage. All together, these effects could have detrimental consequences on fish performances and contribution to recruitment.

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MeSH Term

Animals
Behavior, Animal
Embryo, Nonmammalian
Female
Geologic Sediments
Male
Polycyclic Aromatic Hydrocarbons
Reproduction
Water Pollutants, Chemical
Zebrafish

Chemicals

Polycyclic Aromatic Hydrocarbons
Water Pollutants, Chemical
Journal Article Research Support, Non-U.S. Gov't

Word Cloud

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