Molecular characterization of an Australian serotype 1 Streptococcus pneumoniae outbreak.

M Staples, R M A Graham, A V Jennison, L Ariotti, V Hicks, H Cook, V Krause, C Giele, H V Smith
Author Information
  1. M Staples: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
  2. R M A Graham: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
  3. A V Jennison: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
  4. L Ariotti: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
  5. V Hicks: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
  6. H Cook: Centre for Disease Control, Department of Health, Northern Territory,Australia.
  7. V Krause: Centre for Disease Control, Department of Health, Northern Territory,Australia.
  8. C Giele: Communicable Disease Control Directorate, Public Health Division, Department of Health, Western Australia,Australia.
  9. H V Smith: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.

Abstract

Serotype 1 Streptococcus pneumoniae is a cause of invasive pneumococcal disease (IPD) worldwide and has been associated with IPD outbreaks, while carriage is rarely detected in healthy adults or children. This study details an Australian multi-state and territory outbreak of serotype 1 S. pneumoniae IPD between 2010 and 2012. Molecular characterization demonstrated the outbreak was largely due to the clonal expansion of sequence type 306, MLVA type 261 S. pneumoniae serotype 1.

References

  1. J Clin Microbiol. 2001 Nov;39(11):4190-2 [PMID: 11682558]
  2. Clin Vaccine Immunol. 2009 Feb;16(2):218-21 [PMID: 19091995]
  3. J Infect Dis. 1999 Oct;180(4):1171-6 [PMID: 10479145]
  4. PLoS Med. 2010 Oct 05;7(10): [PMID: 20957191]
  5. Vaccine. 2011 Aug 5;29(34):5740-6 [PMID: 21683112]
  6. J Clin Microbiol. 1996 May;34(5):1176-9 [PMID: 8727898]
  7. J Clin Microbiol. 2006 Jan;44(1):151-9 [PMID: 16390963]
  8. Med J Aust. 1993 Mar 1;158(5):340-2 [PMID: 8474377]
  9. J Clin Microbiol. 2003 Nov;41(11):4966-70 [PMID: 14605125]
  10. J Clin Microbiol. 2001 May;39(5):1827-32 [PMID: 11325998]
  11. J Clin Microbiol. 2006 Jul;44(7):2524-32 [PMID: 16825375]
  12. J Clin Microbiol. 2007 Apr;45(4):1225-33 [PMID: 17267625]
  13. J Infect Dis. 2001 Oct 1;184(7):861-9 [PMID: 11550126]
  14. Microbiology (Reading). 1998 Nov;144 ( Pt 11):3049-3060 [PMID: 9846740]
  15. Vaccine. 2007 Mar 22;25(13):2406-12 [PMID: 17055620]
  16. J Infect Dis. 2008 Dec 15;198(12):1809-17 [PMID: 18959497]
  17. J Med Microbiol. 2008 Jul;57(Pt 7):839-844 [PMID: 18566141]
  18. J Clin Microbiol. 2010 Aug;48(8):2968-71 [PMID: 20534799]
  19. BMC Infect Dis. 2013 Sep 03;13:409 [PMID: 24138669]
  20. J Clin Microbiol. 2008 Mar;46(3):863-8 [PMID: 18160453]
  21. Med J Aust. 2010 Oct 4;193(7):392-6 [PMID: 20919968]
  22. J Clin Microbiol. 1988 Nov;26(11):2465-6 [PMID: 3069867]
  23. BMC Infect Dis. 2010 Oct 23;10:304 [PMID: 20969800]
  24. PLoS Med. 2009 May 26;6(5):e1000081 [PMID: 19468297]
  25. PLoS One. 2011;6(5):e19668 [PMID: 21637335]
  26. J Clin Microbiol. 1995 Oct;33(10):2759-62 [PMID: 8567920]

Grants

  1. /Wellcome Trust

MeSH Term

Adolescent
Adult
Australia
Child
Child, Preschool
Disease Outbreaks
Humans
Middle Aged
Models, Statistical
Molecular Epidemiology
Pneumococcal Infections
Streptococcus pneumoniae
Young Adult

Word Cloud

Created with Highcharts 10.0.01pneumoniaeIPDoutbreakserotypeStreptococcusAustralianSMolecularcharacterizationtypeSerotypecauseinvasivepneumococcaldiseaseworldwideassociatedoutbreakscarriagerarelydetectedhealthyadultschildrenstudydetailsmulti-stateterritory20102012demonstratedlargelydueclonalexpansionsequence306MLVA261

Similar Articles

Cited By