Molecular characterization of an Australian serotype 1 Streptococcus pneumoniae outbreak.
M Staples, R M A Graham, A V Jennison, L Ariotti, V Hicks, H Cook, V Krause, C Giele, H V Smith
Author Information
M Staples: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
R M A Graham: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
A V Jennison: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
L Ariotti: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
V Hicks: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
H Cook: Centre for Disease Control, Department of Health, Northern Territory,Australia.
V Krause: Centre for Disease Control, Department of Health, Northern Territory,Australia.
C Giele: Communicable Disease Control Directorate, Public Health Division, Department of Health, Western Australia,Australia.
H V Smith: Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
中文译文
English
Serotype 1 Streptococcus pneumoniae is a cause of invasive pneumococcal disease (IPD) worldwide and has been associated with IPD outbreaks, while carriage is rarely detected in healthy adults or children. This study details an Australian multi-state and territory outbreak of serotype 1 S. pneumoniae IPD between 2010 and 2012. Molecular characterization demonstrated the outbreak was largely due to the clonal expansion of sequence type 306, MLVA type 261 S. pneumoniae serotype 1.
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/Wellcome Trust
Adolescent
Adult
Australia
Child
Child, Preschool
Disease Outbreaks
Humans
Middle Aged
Models, Statistical
Molecular Epidemiology
Pneumococcal Infections
Streptococcus pneumoniae
Young Adult