Healthcare workers as vectors of infectious diseases.

R Huttunen, J Syrjänen
Author Information
  1. R Huttunen: Department of Internal Medicine, Tampere University Hospital, Box 2000, 33521, Tampere, Finland, reetta.huttunen@uta.fi.

Abstract

Nosocomial infections cause considerable morbidity and mortality. Healthcare workers (HCWs) may serve as vectors of many infectious diseases, many of which are not often primarily considered as healthcare-associated. The probability of pathogen transmission to patients depends on several factors, such as the characteristics of a pathogen, HCW and patient. Pathogens with high transmission potential from HCWs to patients include norovirus, respiratory infections, measles and influenza. In contrast, human immunodeficiency virus (HIV) and viral hepatitis are unlikely to be transferred. The prevention of HCW-associated transmission of pathogens include systematic vaccinations towards preventable diseases, continuous education, hand hygiene surveillance, active feedback and adequate staff resources.

References

  1. J Infect. 2012 Jan;64(1):1-18 [PMID: 22120112]
  2. J Antimicrob Chemother. 2009 Sep;64 Suppl 1:i11-7 [PMID: 19675013]
  3. MMWR Morb Mortal Wkly Rep. 2011 Dec 2;60(47):1605-10 [PMID: 22129994]
  4. BMC Infect Dis. 2013 Oct 04;13:459 [PMID: 24090343]
  5. BMC Infect Dis. 2013 Feb 22;13:98 [PMID: 23432927]
  6. Trop Med Int Health. 2010 Oct;15(10):1179-84 [PMID: 20831672]
  7. Am J Infect Control. 2010 Jun;38(5 Suppl 1):S25-33 [PMID: 20569853]
  8. Infect Control Hosp Epidemiol. 2006 Jun;27(6):581-5 [PMID: 16755477]
  9. Emerg Infect Dis. 2011 Mar;17(3):488-94 [PMID: 21392441]
  10. Clin Vaccine Immunol. 2014 Feb;21(2):119-25 [PMID: 24256623]
  11. BMC Infect Dis. 2010 Aug 20;10:247 [PMID: 20727178]
  12. Vaccine. 2014 Aug 27;32(38):4844-8 [PMID: 24120676]
  13. Clin Infect Dis. 2001 Feb 1;32(3):352-7 [PMID: 11170941]
  14. MMWR Recomm Rep. 1991 Jul 12;40(RR-8):1-9 [PMID: 1648165]
  15. Crit Care Med. 2010 Jul;38(7):1521-8; quiz 1529 [PMID: 20473146]
  16. Nurs Crit Care. 2010 May-Jun;15(3):109-11 [PMID: 20500648]
  17. J Hosp Infect. 2001 Aug;48 Suppl A:S40-6 [PMID: 11759025]
  18. J Infect Public Health. 2012 Apr;5(2):127-32 [PMID: 22541258]
  19. Expert Rev Vaccines. 2010 Mar;9(3):277-83 [PMID: 20218856]
  20. Antiviral Res. 2003 Oct;60(2):79-85 [PMID: 14638402]
  21. Evid Rep Technol Assess (Full Rep). 2007 Mar;(151):1-115 [PMID: 17764206]
  22. Infect Control Hosp Epidemiol. 2014 Jan;35(1):10-5 [PMID: 24334792]
  23. Cochrane Database Syst Rev. 2006 Jul 19;(3):CD005187 [PMID: 16856082]
  24. Infect Control Hosp Epidemiol. 2006 Jun;27(6):541-5 [PMID: 16755471]
  25. PLoS One. 2012;7(3):e32731 [PMID: 22427871]
  26. Infect Control Hosp Epidemiol. 2008 Feb;29(2):149-54 [PMID: 18179370]
  27. Am J Epidemiol. 1981 Feb;113(2):126-32 [PMID: 6258425]
  28. Infect Control. 1986 Oct;7(10):487-90 [PMID: 3640736]
  29. Am J Infect Control. 2007 Aug;35(6):412-6 [PMID: 17660013]
  30. Clin Infect Dis. 2002 Dec 1;35(11):1353-9 [PMID: 12439798]
  31. Epidemiology. 2012 Mar;23(2):277-84 [PMID: 22317811]
  32. J Hosp Infect. 2009 Dec;73(4):305-15 [PMID: 19720430]
  33. Vaccine. 2009 Jun 24;27(31):4240-3 [PMID: 19481314]
  34. Lancet. 2007 Dec 15;370(9604):2030-43 [PMID: 17719083]
  35. Infect Control Hosp Epidemiol. 1994 Jun;15(6):411-5 [PMID: 8083507]
  36. Clin Infect Dis. 2011 Feb 15;52(4):e56-93 [PMID: 21258094]
  37. BMC Infect Dis. 2010 Feb 23;10:35 [PMID: 20178573]
  38. J Clin Microbiol. 1986 Jul;24(1):36-40 [PMID: 3013932]
  39. Arch Intern Med. 2011 Jan 24;171(2):151-7 [PMID: 21263105]
  40. MMWR Recomm Rep. 2011 Nov 25;60(RR-7):1-45 [PMID: 22108587]
  41. Int J Tuberc Lung Dis. 2011 Nov;15(11):1510-4, i [PMID: 22008765]
  42. Infect Control Hosp Epidemiol. 2002 Jan;23(1):23-6 [PMID: 11868888]
  43. Vaccine. 2012 Jul 27;30(35):5179-90 [PMID: 22709953]
  44. J Clin Microbiol. 2004 Oct;42(10):4468-72 [PMID: 15472295]
  45. Emerg Infect Dis. 2011 Aug;17(8):1421-9 [PMID: 21801619]
  46. Lancet Infect Dis. 2002 Mar;2(3):145-55 [PMID: 11944184]
  47. J Infect. 2012 Mar;64(3):319-24 [PMID: 22198739]
  48. MMWR Morb Mortal Wkly Rep. 2008 Jun 6;57(22):600-3 [PMID: 18528316]
  49. Scand J Gastroenterol Suppl. 2004;(241):45-9 [PMID: 15696849]
  50. Clin Infect Dis. 2012 Apr;54(7):931-7 [PMID: 22291099]
  51. BMC Infect Dis. 2010 Oct 28;10:313 [PMID: 21029452]
  52. Clin Infect Dis. 2012 Aug;55(3):426-31 [PMID: 22523266]
  53. Med Care. 2007 Dec;45(12):1195-204 [PMID: 18007170]
  54. Am J Infect Control. 2010 Aug;38(6):486-8 [PMID: 20176412]
  55. J Hosp Infect. 2014 Mar;86(3):188-93 [PMID: 24468292]
  56. J Hosp Infect. 2012 Feb;80(2):144-9 [PMID: 22154781]
  57. Curr Opin Infect Dis. 2008 Aug;21(4):337-43 [PMID: 18594283]
  58. Infect Control Hosp Epidemiol. 2008 Jul;29(7):600-6 [PMID: 18624667]
  59. MMWR Recomm Rep. 2012 Jul 6;61(RR-3):1-12 [PMID: 22763928]
  60. Clin Infect Dis. 2007 Sep 1;45(5):534-40 [PMID: 17682985]
  61. Am J Infect Control. 2007 Sep;35(7):448-54 [PMID: 17765556]
  62. J Hosp Infect. 1995 Jun;30 Suppl:140-55 [PMID: 7560944]
  63. Lancet Infect Dis. 2012 Jan;12(1):36-44 [PMID: 22032844]
  64. Euro Surveill. 2010 Nov 04;15(44): [PMID: 21087586]
  65. J Hosp Infect. 2006 Oct;64(2):100-14 [PMID: 16916564]
  66. Clin Infect Dis. 2014 Jan;58(1):50-7 [PMID: 24046301]
  67. J Hosp Infect. 2011 Apr;77(4):285-9 [PMID: 21292349]
  68. BMC Infect Dis. 2006 Aug 16;6:130 [PMID: 16914034]
  69. Am J Respir Crit Care Med. 2014 Jan 1;189(1):77-87 [PMID: 24299555]
  70. Clin Infect Dis. 2000 Aug;31(2):578-85 [PMID: 10987724]
  71. Infect Control Hosp Epidemiol. 2013 Apr;34(4):373-8 [PMID: 23466910]
  72. J Clin Microbiol. 2006 Jan;44(1):218-21 [PMID: 16390973]
  73. Infect Control Hosp Epidemiol. 2006 Nov;27(11):1178-83 [PMID: 17080374]
  74. Infect Control Hosp Epidemiol. 2000 Feb;21(2):80-5 [PMID: 10697282]
  75. J Perinatol. 2008 May;28(5):319-23 [PMID: 18368056]
  76. J Hosp Infect. 2008 Jul;69(3):288-94 [PMID: 18439716]
  77. Clin Infect Dis. 2001 Aug 1;33(3):317-23 [PMID: 11438896]
  78. J Hosp Infect. 2003 Oct;55(2):131-6 [PMID: 14529638]
  79. Vaccine. 2011 Nov 28;29(51):9557-62 [PMID: 21964058]
  80. Lancet Infect Dis. 2008 May;8(5):289-301 [PMID: 18471774]
  81. Ann Intern Med. 2010 Oct 19;153(8):516-22 [PMID: 20956708]
  82. Infect Control Hosp Epidemiol. 1996 Oct;17(10):694-705 [PMID: 8899447]
  83. Infect Control Hosp Epidemiol. 2012 Aug;33(8):761-7 [PMID: 22759542]
  84. Lancet. 2000 Oct 14;356(9238):1307-12 [PMID: 11073019]
  85. Infect Control Hosp Epidemiol. 2009 Sep;30(9):924-5 [PMID: 19653823]
  86. Infect Control Hosp Epidemiol. 2004 Mar;25(3):210-5 [PMID: 15061412]
  87. Infect Control Hosp Epidemiol. 2005 Feb;26(2):213-5 [PMID: 15756895]
  88. J Hosp Infect. 2013 Dec;85(4):243-8 [PMID: 24156850]
  89. J Clin Virol. 2003 Aug;27(3):213-30 [PMID: 12878084]
  90. Infect Control Hosp Epidemiol. 2011 Jul;32(7):687-99 [PMID: 21666400]
  91. J Hosp Infect. 2012 Sep;82(1):36-9 [PMID: 22784489]
  92. J Hosp Infect. 2012 Feb;80(2):162-7 [PMID: 22188630]
  93. PLoS Med. 2011 Mar;8(3):e1001012 [PMID: 21445325]
  94. Infect Control Hosp Epidemiol. 2007 Apr;28(4):430-4 [PMID: 17385149]
  95. Int J Antimicrob Agents. 2008 Feb;31(2):99-106 [PMID: 18164908]
  96. Clin Infect Dis. 2004 Aug 15;39(4):459-64 [PMID: 15356805]
  97. Infect Control Hosp Epidemiol. 2008 Jul;29(7):583-9 [PMID: 18549314]
  98. Vaccine. 2012 Jun 8;30(27):3996-4001 [PMID: 22521843]
  99. Am J Infect Control. 2011 Aug;39(6):488-94 [PMID: 21288599]

MeSH Term

Animals
Communicable Disease Control
Communicable Diseases
Cross Infection
Disease Transmission, Infectious
Disease Vectors
Health Facilities
Health Personnel
Humans