Fecal microbiota transplantation in children with recurrent Clostridium difficile infection.

Anne Pierog, Ali Mencin, Norelle Rizkalla Reilly
Author Information
  1. Anne Pierog: From the Columbia University Medical Center, Division of Pediatric Gastroenterology, Hepatology and Nutrition, New York, NY.

Abstract

Clostridium difficile eradication using fecal microbiota transplantation (FMT) has been successful in adults but little information is available in pediatrics. We report 6 pediatric patients with refractory C. difficile cured by FMT with no recurrences to date. Our results demonstrate that FMT can be an effective treatment for refractory C. difficile infection in pediatrics. Long-term safety and efficacy need to be studied.

MeSH Term

Biological Therapy
Child
Child, Preschool
Clostridioides difficile
Enterocolitis, Pseudomembranous
Feces
Female
Humans
Infant
Male
Microbiota
Recurrence
Retreatment
Young Adult