OpenLB
Open Library of Bioscience
Advanced Search
Journal of perinatology : official journal of the California Perinatal Association
Nov, 2014;34 (11): 805-10.

Decolonization to prevent Staphylococcus aureus transmission and infections in the neonatal intensive care unit.

V O Popoola, A M Milstone
Author Information
  1. V O Popoola: Department of Pediatrics and Epidemiology, Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  2. A M Milstone: 1] Department of Pediatrics and Epidemiology, Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA [2] Department of Hospital Epidemiology and Infection Control, Johns Hopkins Hospital, Baltimore, MD, USA.
PMID: 25010222 DOI: 10.1038/jp.2014.128

Abstract

Staphylococcus aureus (S. aureus) continues to be a leading cause of outbreaks and health-care-associated infections in neonatal intensive care units. In the first few months of life, many neonates acquire S. aureus as part of their delicate and evolving microbiota. Neonates that asymptomatically acquire S. aureus colonization are at increased risk of developing a subsequent S. aureus infection. This review discusses the epidemiology and prevention of S. aureus disease in neonates and how decolonization to eradicate S. aureus may decrease S. aureus transmission and infections in the neonatal intensive care unit.

References

  1. Cochrane Database Syst Rev. 2008 Oct 08;(4):CD006216 [PMID: 18843708]
  2. Pediatrics. 2006 Aug;118(2):469-74 [PMID: 16882797]
  3. N Engl J Med. 2010 Jan 7;362(1):9-17 [PMID: 20054045]
  4. Clin Infect Dis. 2013 Nov;57(10):1458-60 [PMID: 23943821]
  5. J Perinatol. 2013 Apr;33(4):313-8 [PMID: 22918547]
  6. Pediatrics. 2012 Apr;129(4):e914-22 [PMID: 22412036]
  7. Am J Infect Control. 2011 Feb;39(1):35-41 [PMID: 21281885]
  8. Pediatr Infect Dis J. 1998 Apr;17(4):329-34 [PMID: 9576389]
  9. J Hosp Infect. 2012 Sep;82(1):56-7 [PMID: 22854355]
  10. Infect Control Hosp Epidemiol. 2014 Apr;35(4):412-8 [PMID: 24602947]
  11. Am J Infect Control. 2009 Apr;37(3):195-200 [PMID: 19181423]
  12. Infect Control Hosp Epidemiol. 2010 Jun;31(6):613-9 [PMID: 20420500]
  13. Pediatrics. 2012 May;129(5):e1252-9 [PMID: 22473373]
  14. Am J Infect Control. 2007 Dec;35(10 Suppl 2):S165-93 [PMID: 18068814]
  15. Clin Infect Dis. 2009 Sep 15;49(6):935-41 [PMID: 19673644]
  16. Early Hum Dev. 2012 May;88 Suppl 2:S69-74 [PMID: 22633519]
  17. J Hosp Infect. 2000 Oct;46(2):123-9 [PMID: 11049705]
  18. Nat Immunol. 2013 Jul;14(7):646-53 [PMID: 23778791]
  19. Infect Control Hosp Epidemiol. 1996 Dec;17(12):811-3 [PMID: 8985769]
  20. Pediatr Infect Dis J. 2009 Jul;28(7):577-81 [PMID: 19478687]
  21. Am J Infect Control. 2009 Sep;37(7):580-6 [PMID: 19535174]
  22. Am J Infect Control. 2010 Oct;38(8):607-11 [PMID: 20570396]
  23. Infect Control Hosp Epidemiol. 2003 May;24(5):317-21 [PMID: 12785403]
  24. Clin Infect Dis. 2007 Sep 1;45(5):541-7 [PMID: 17682986]
  25. Infect Control Hosp Epidemiol. 2010 Jul;31(7):766-8 [PMID: 20470034]
  26. N Engl J Med. 2013 Jun 13;368(24):2255-65 [PMID: 23718152]
  27. Infect Control Hosp Epidemiol. 2010 May;31(5):558-60 [PMID: 20334509]
  28. Pediatr Infect Dis J. 2006 Aug;25(8):665-75 [PMID: 16874163]
  29. Am J Epidemiol. 2013 Jun 1;177(11):1306-13 [PMID: 23592544]
  30. Infect Control Hosp Epidemiol. 2012 Oct;33(10):1024-30 [PMID: 22961022]
  31. JAMA Otolaryngol Head Neck Surg. 2013 Dec;139(12):1328-38 [PMID: 24177790]
  32. PLoS One. 2011;6(8):e23001 [PMID: 21857979]
  33. Infect Control Hosp Epidemiol. 2000 Nov;21(11):718-23 [PMID: 11089656]
  34. Infect Control Hosp Epidemiol. 2012 Dec;33(12):1200-6 [PMID: 23143356]
  35. Infect Control Hosp Epidemiol. 2005 Jul;26(7):616-21 [PMID: 16092741]
  36. Clin Infect Dis. 2011 Nov;53(9):853-9 [PMID: 21878424]
  37. J Clin Microbiol. 2006 Nov;44(11):4234-6 [PMID: 16957041]
  38. Trends Immunol. 2013 Jun;34(6):299-306 [PMID: 23643444]
  39. Infect Control Hosp Epidemiol. 2010 Feb;31(2):177-82 [PMID: 20001732]
  40. Am J Infect Control. 2009 Mar;37(2):106-10 [PMID: 18945520]
  41. Eur J Clin Microbiol Infect Dis. 2011 Jul;30(7):909-13 [PMID: 21298461]
  42. Pediatrics. 2011 Aug;128(2):e348-57 [PMID: 21768312]
  43. Infect Control Hosp Epidemiol. 2010 Aug;31(8):779-83 [PMID: 20594110]
  44. Infect Control Hosp Epidemiol. 2007 Oct;28(10):1155-61 [PMID: 17828692]
  45. Infect Control Hosp Epidemiol. 2011 Apr;32(4):398-400 [PMID: 21460494]
  46. Infect Control Hosp Epidemiol. 2006 Feb;27(2):139-45 [PMID: 16465630]
  47. J Perinatol. 2012 Jan;32(1):4-9 [PMID: 22031047]
  48. JAMA. 2004 Nov 17;292(19):2357-65 [PMID: 15547163]
  49. Infect Control Hosp Epidemiol. 2002 Nov;23(11):677-82 [PMID: 12452296]
  50. Arch Dis Child Fetal Neonatal Ed. 2005 Jan;90(1):F10 [PMID: 15613563]
  51. Eur J Pediatr. 1996 Mar;155(3):194-9 [PMID: 8929727]
  52. J Perinatol. 2013 Oct;33(10):768-71 [PMID: 23702618]
  53. Infect Control Hosp Epidemiol. 2010 Aug;31(8):846-9 [PMID: 20586654]
  54. Nat Med. 2013 Jun;19(6):713-21 [PMID: 23708291]
  55. PLoS One. 2013;8(1):e54898 [PMID: 23382995]
  56. Am J Infect Control. 2007 Apr;35(3):172-6 [PMID: 17433940]
  57. Pediatr Dermatol. 2010 Nov-Dec;27(6):676-8 [PMID: 21510025]
  58. J Antimicrob Chemother. 2013 May;68(5):992-9 [PMID: 23288405]
  59. J Paediatr Child Health. 1992 Aug;28(4):306-8 [PMID: 1497958]
  60. Science. 2013 Nov 22;342(6161):967-70 [PMID: 24264989]
  61. Am J Epidemiol. 1996 Mar 1;143(5):496-504 [PMID: 8610665]
  62. Dev Med Child Neurol. 2012 Mar;54(3):240-6 [PMID: 22188215]
  63. Ann Intern Med. 2008 Mar 18;148(6):409-18 [PMID: 18347349]

MeSH Term

Anti-Bacterial Agents
Asymptomatic Diseases
Carrier State
Cross Infection
Humans
Infant, Newborn
Intensive Care Units, Neonatal
Mupirocin
Risk Assessment
Staphylococcal Infections

Chemicals

Anti-Bacterial Agents
Mupirocin
Journal Article Research Support, Non-U.S. Gov't
Article has an altmetric score of 4

Word Cloud

Created with Highcharts 10.0.0aureusSinfectionsneonatalintensivecareStaphylococcusneonatesacquiretransmissionunitcontinuesleadingcauseoutbreakshealth-care-associatedunitsfirstmonthslifemanypartdelicateevolvingmicrobiotaNeonatesasymptomaticallycolonizationincreasedriskdevelopingsubsequentinfectionreviewdiscussesepidemiologypreventiondiseasedecolonizationeradicatemaydecreaseDecolonizationprevent

Similar Articles

Cited By